product summary
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company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN IgD
catalog :
MBS211273
quantity :
0.5 mg
price :
475 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
IADB6
application :
ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS211273
products type :
Antibody
products full name :
MOUSE ANTI HUMAN IgD
products short name :
IgD
other names :
Ig delta chain C region, partial; Ig delta chain C region; immunoglobulin heavy constant delta
products gene name :
IgD
other gene names :
IGHD; IGHD
uniprot entry name :
IGHD_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
IADB6
host :
Mouse
sequence length :
430
specificity :
This product is specific for the delta chain of human IgD, it may also cross react with IgD from other species.
form :
Purified. Purified IgG - liquid
concentration :
IgG concentration 0.5mg/ml
storage stability :
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from the date of despatch.
tested application :
ELISA (EIA)
other info2 :
Buffer Solution: Borate buffered saline. Target Species: Human
products description :
This product is specific for the delta chain of human IgD, it may also cross react with IgD from other species.
ncbi gi num :
193806360
ncbi acc num :
P01880.2
uniprot acc num :
P01880
ncbi mol weight :
47,401 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Antigen Activates B Cell Receptor (BCR) Leading To Generation Of Second Messengers Pathway (576249); Immune System Pathway (106386); Signaling By The B Cell Receptor (BCR) Pathway (576248)
uniprot summary :
IGHD: IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD. 2 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 14q32.33. Cellular Component: integral to membrane; plasma membrane. Molecular Function: antigen binding. Biological Process: immune response
size1 :
0.5 mg
price1 :
475 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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