product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD226:Low Endotoxin
catalog :
MBS211218
quantity :
0.5 mg
price :
550 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DX11
reactivity :
human
application :
immunoprecipitation, flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS211218
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD226:Low Endotoxin
products short name :
CD226
other names :
CD226 antigen isoform a; CD226 antigen; CD226 antigen; DNAX accessory molecule 1; DNAX accessory molecule-1; T lineage-specific activation antigen 1 antigen; adhesion glycoprotein; platelet and T cell activation antigen 1; CD226 molecule; DNAX accessory molecule 1; DNAM-1; CD_antigen: CD226
products gene name :
CD226
other gene names :
CD226; CD226; PTA1; DNAM1; DNAM-1; TLiSA1; DNAM1; DNAM-1
uniprot entry name :
CD226_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
DX11
host :
Mouse
sequence length :
336
form :
Low Endotoxin. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at -20 degree C only. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS), Functional Assays (FN), Immunoprecipitation (IP)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 1 x 106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/200
other info1 :
Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Immunogen: Human cytotoxic T lymphocyte clone. Fusion Partners: Spleen cells from immunised BALB/c mouse were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human CD226 antibody, clone DX11 recognizes human CD226, a 65kDa glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells. CD226 is also expressed by a subset of CD3 positive thymocytes. Mouse anti Human CD226 antibody, clone DX11 is reported to inhibit T- and NK cell mediated cytotoxicity against tumor cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells (Kojima et al. 2003).
ncbi gi num :
171460997
ncbi acc num :
NP_006557.2
ncbi gb acc num :
NM_006566.3
uniprot acc num :
Q15762
ncbi mol weight :
38,614 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Immune System Pathway 106386!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 106413
ncbi summary :
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
size :
0.5 mg
price :
550 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!