product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD61:FITC
catalog :
MBS211080
quantity :
0.1 mg
price :
365 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
reactivity :
human
application :
flow cytometry, FACS
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS211080
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD61:FITC
products short name :
CD61
other names :
integrin beta-3; Integrin beta-3; integrin beta-3; platelet membrane glycoprotein IIIa; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); Platelet membrane glycoprotein IIIa; GPIIIa; CD_antigen: CD61
products gene name :
CD61
other gene names :
ITGB3; ITGB3; GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; GP3A; GPIIIa
uniprot entry name :
ITB3_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
PM6/13
host :
Mouse
sequence length :
784
form :
FITC. Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
concentration :
IgG concentration 0.1mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood. Flow Cytometry: Maximum Dilution: Neat
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. Preparation: Purified IgG prepared by ion exchange chromatography
other info2 :
Immunogen: Platelet plasma membrane. Fusion Partners: Spleen cells from immunised mice were fused with cells of the mouse SP2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human CD61 antibody, clone PM6/13 recognizes a 105kD glycoprotein, which is the integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin. Mouse anti Human CD61 antibody, clone PM6/13 has been reported to inhibit binding of fibronectin to activated human platelets. In functional studies it can be used to inhibit agonist induced platelet aggregation.
ncbi gi num :
47078292
ncbi acc num :
NP_000203.2
ncbi gb acc num :
NM_000212.2
uniprot acc num :
P05106
ncbi mol weight :
86,694 Da
ncbi pathways :
Arf6 Signaling Events Pathway 138034!!Arrhythmogenic Right Ventricular Cardiomyopathy Pathway 672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129!!Axon Guidance Pathway 105688!!Cell Surface Interactions At The Vascular Wall Pathway 106062!!Developmental Biology Pathway 477129!!Dilated Cardiomyopathy Pathway 121494!!Dilated Cardiomyopathy Pathway 121285!!ECM Proteoglycans Pathway 833812
ncbi summary :
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
365 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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