MOUSE ANTI HUMAN CD36:FITC | MyBioSource MBS211078 product information

product summary

request information :

company name :

MyBioSource

product type :

antibody

product name :

MOUSE ANTI HUMAN CD36:FITC

catalog :

MBS211078

quantity :

0.1 mg

price :

365 USD

clonality :

monoclonal

host :

mouse

conjugate :

FITC

reactivity :

human

application :

FACS, flow cytometry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS211078

products type :

Antibody

products full name :

MOUSE ANTI HUMAN CD36:FITC

products short name :

CD36

other names :

platelet glycoprotein 4 isoform 1; Platelet glycoprotein 4; platelet glycoprotein 4; CD36 antigen (collagen type I receptor, thrombospondin receptor); GPIIIB; PAS IV; PAS-4 protein; cluster determinant 36; fatty acid translocase; glycoprotein IIIb; leukocyte differentiation antigen CD36; platelet glycoprotein IV; scavenger receptor class B, member 3; CD36 molecule (thrombospondin receptor); Fatty acid translocase; FAT; Glycoprotein IIIb; GPIIIB; Leukocyte differentiation antigen CD36; PAS IV; PAS-4; Platelet collagen receptor; Platelet glycoprotein IV; GPIV; Thrombospondin receptor; CD_antigen: CD36

products gene name :

CD36

other gene names :

CD36; CD36; FAT; GP4; GP3B; GPIV; CHDS7; PASIV; SCARB3; BDPLT10; GP3B; GP4; FAT; GPIIIB; GPIV

uniprot entry name :

CD36_HUMAN

clonality :

Monoclonal

isotype :

IgM

clone :

SMØ

host :

Mouse

sequence length :

412

form :

FITC. Purified IgM conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid

concentration :

IgM concentration 0.1 mg/ml

storage stability :

Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

Flow cytometry (FC/FACS)

app notes :

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: Neat; Maximum Dilution: 1/5

other info1 :

Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. Preparation: Purified IgM prepared by ammonium sulphate precipitation from tissue culture supernatant

other info2 :

Immunogen: Human tonsil and peripheral blood mononuclear cells. Fusion Partners: Spleen cells from immunised mice were fused with cells of the NSI mouse myeloma line. Buffer Solution: Phosphate buffered saline. Target Species: Human

products description :

Mouse anti Human CD36 antibody, clone SM˜ recognizes the CD36 antigen, an 88kD cell surface glycoprotein expressed by platelets, monocytes/macrophages and also by some microvascular endothelium and erythroid precursors. CD36 is the receptor for thrombospondin. When expressed by monocytes and macrophages, CD36 acts as a receptor for oxidized LDL and for apoptotic polymorphonuclear cells. Mouse anti Human CD36 antibody, clone SM˜ partially inhibits collagen induced platelet aggregation and macrophage ingestion of apoptotic human neutrophils. It has been reported that this antibody may activate platelets as measured by fibrinogen binding, P-Selectin expression and Annexin V binding - for further details please contact our Technical Services team. Mouse anti Human CD36 antibody, clone SM˜ is also reported to block interaction of oxidised low-density lipoprotein (OXLDL) with CD36 (Sugihara et al.1992).

ncbi gi num :

48375178

ncbi acc num :

NP_000063.2

ncbi gb acc num :

NM_000072.3

uniprot acc num :

P16671

ncbi mol weight :

46,090 Da

ncbi pathways :

AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Activated TLR4 Signalling Pathway 106400!!Adaptive Immune System Pathway 366160!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Antigen Processing-Cross Presentation Pathway 477122!!Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Class I MHC Mediated Antigen Processing Presentation Pathway 366161!!Cross-presentation Of Particulate Exogenous Antigens (phagosomes) Pathway 477123

ncbi summary :

The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]

size :

0.1 mg

price :

365 USD

more info or order :

MyBioSource product webpage