RAT ANTI MOUSE CD13:FITC | MyBioSource MBS210863 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

RAT ANTI MOUSE CD13:FITC

catalog :

MBS210863

quantity :

0.1 mg

price :

370 USD

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

[R3-63]

reactivity :

mouse

application :

flow cytometry, FACS

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS210863

products type :

Antibody

products full name :

RAT ANTI MOUSE CD13:FITC

products short name :

[CD13]

products name syn :

[Lap1, Lap-1]

other names :

[aminopeptidase N; Aminopeptidase N; aminopeptidase N; alanyl aminopeptidase; aminopeptidase M; aminopeptidase N/CD13; membrane protein p161; microsomal aminopeptidase; alanyl (membrane) aminopeptidase; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Membrane protein p161; Microsomal aminopeptidase; CD_antigen: CD13]

products gene name :

[CD13]

other gene names :

[Anpep; Anpep; Apn; AP-M; AP-N; Cd13; P150; Lap-1; Lap1; AP-N; mAPN; AP-M]

uniprot entry name :

AMPN_MOUSE

clonality :

Monoclonal

isotype :

IgG2a

clone :

[R3-63]

host :

Rat

sequence length :

966

form :

FITC. Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid

concentration :

IgG concentration 0.1 mg/ml

storage stability :

Store at 4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.

tested application :

Flow cytometry (FC/FACS)

app notes :

Neat- 1/5. Use 10 uL of the suggested working dilution to label 10 6 cells in 100 uL.

other info1 :

Preservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant. Buffer Solution: Phosphate buffered saline

other info2 :

Immunogen: Mouse intestinal APN. Fusion Partners: Spleen cells from immunised mice were fused with cells of the IR983F rat myeloma cell line. Target Species: Mouse

products description :

Rat anti Mouse CD13 antibody, clone R3-63 recognizes mouse aminopeptidase N (APN), a cell surface protein homologous with human CD13. In the mouse, CD13 is a non-covalently linked homodimer of approximately 150kDa subunits expressed by a variety of cells including monocytes, macrophages, dendritic cell and veiled cells. Rat anti Mouse CD13 antibody, clone R3-63 has been reported to block mouse APN enzyme activity (Kamoun et al. 2009).

ncbi gi num :

225637487

ncbi acc num :

NP_032512.2

ncbi gb acc num :

NM_008486.2

uniprot acc num :

P97449

ncbi pathways :

Glutathione And One Carbon Metabolism Pathway (760633); Glutathione Metabolism Pathway (83172); Glutathione Metabolism Pathway (198381); Glutathione Metabolism Pathway (343); Hematopoietic Cell Lineage Pathway (83275); Hematopoietic Cell Lineage Pathway (489); Metabolic Pathways (132962); Metabolism Of Angiotensinogen To Angiotensins Pathway (1110258); Metabolism Of Proteins Pathway (1110188); Peptide Hormone Metabolism Pathway (1110255)

uniprot summary :

CD13: Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types including small intestinal and tubular epithelial cells, macrophages, granulocytes and synaptic membranes from the CNS. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection. Belongs to the peptidase M1 family. Protein type: Protease; Receptor, misc.; EC 3.4.11.2; Other Amino Acids Metabolism - glutathione; Membrane protein, integral. Cellular Component: extracellular space; membrane; lysosomal membrane; integral to membrane; ER-Golgi intermediate compartment; vesicle membrane; external side of plasma membrane. Molecular Function: peptidase activity; zinc ion binding; metallopeptidase activity; hydrolase activity; metal ion binding; aminopeptidase activity; peptide binding. Biological Process: multicellular organismal development; aromatic compound metabolic process; angiogenesis; cell differentiation; proteolysis

size1 :

0.1 mg

price1 :

370 USD

more info or order :

MyBioSource product webpage