product summary
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company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI RAT CD31:FITC
catalog :
MBS210660
quantity :
0.5 mg
price :
625 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
TLD-3A12
reactivity :
rat
application :
flow cytometry, FACS
more info or order :
product information
catalog number :
MBS210660
products type :
Antibody
products full name :
MOUSE ANTI RAT CD31:FITC
products short name :
CD31
other names :
platelet endothelial cell adhesion molecule; Platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule; PECAM-1; platelet/endothelial cell adhesion molecule 1; CD_antigen: CD31
products gene name :
CD31
other gene names :
Pecam1; Pecam1; CD31; Pecam; Pecam; PECAM-1
uniprot entry name :
PECA1_RAT
clonality :
Monoclonal
isotype :
IgG1
clone :
TLD-3A12
host :
Mouse
sequence length :
678
form :
FITC. Purified IgG conjugated to Fluorescein Isothiocyanate Isomer 1 (FITC) - liquid
concentration :
IgG concentration 0.5 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. Flow Cytometry: Minimum Dilution: 1/50; Maximum Dilution: 1/100
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. Preparation: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Rat
products description :
Mouse anti Rat CD31 antibody, clone TLD-3A12 recognizes rat PECAM-1 (CD31), a 661 amino acid type 1 transmembrane protein expressed primarily on endothelial cells, platelets and leucocytes. Clone TLD-3A12 has been shown to partially block the proliferative response of antigen-specific CD4+ T cells to antigen-presenting cells and relevant antigen (Stevenson, K.S. et al.2009). This clone has been reported as suitable for use in IHC on formalin-fixed paraffin-embedded sections pre-treated with 0.2M boric acid, pH7.0. (Wilson et al. 2007). Mouse anti Rat CD31, clone TLD-3A12 has been shown to be cross-reactive with endothelial cells derived from rhesus macaque (Maclean et al. 2001)
ncbi gi num :
75832033
ncbi acc num :
NP_113779.1
ncbi gb acc num :
NM_031591.1
uniprot acc num :
Q3SWT0
ncbi mol weight :
76,189 Da
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway (83461); Cell Adhesion Molecules (CAMs) Pathway (480); Leukocyte Transendothelial Migration Pathway (83475); Leukocyte Transendothelial Migration Pathway (494); Malaria Pathway (152662); Malaria Pathway (152657)
ncbi summary :
cell adhesion molecule, also intracellular signaling molecule; may mediate leukocyte adhesion and migration, angiogenesis, and thrombosis [RGD, Feb 2006]
uniprot summary :
PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues. Protein type: Cell adhesion; Contractile; Motility/polarity/chemotaxis; Membrane protein, integral; Vesicle; G protein, monomeric, non-Rab; Cell surface. Cellular Component: extracellular space; smooth muscle contractile fiber; cell surface; membrane; integral to membrane; plasma membrane; intracellular; cell junction; external side of plasma membrane; lipid raft. Molecular Function: protein binding. Biological Process: negative regulation of peptidyl-tyrosine phosphorylation; positive regulation of tyrosine phosphorylation of Stat5 protein; wound healing; negative regulation of actin filament polymerization; positive regulation of leukocyte migration; response to cytokine stimulus; diapedesis; cell adhesion; regulation of cell migration; phagocytosis; Rho protein signal transduction
size1 :
0.5 mg
price1 :
625 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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