This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN CD20
catalog :
MBS210557
quantity :
1 mL
price :
485 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
L26
reactivity :
human, Rhesus monkey
product information
catalog number :
MBS210557
products type :
Antibody
products full name :
MOUSE ANTI HUMAN CD20
products short name :
CD20
other names :
B-lymphocyte antigen CD20; B-lymphocyte antigen CD20; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; membrane-spanning 4-domains, subfamily A, member 1; B-lymphocyte surface antigen B1; Bp35; Leukocyte surface antigen Leu-16; Membrane-spanning 4-domains subfamily A member 1; CD_antigen: CD20
products gene name :
CD20
other gene names :
MS4A1; MS4A1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; CD20
uniprot entry name :
CD20_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
L26
host :
Mouse
reactivity :
Cynomolgus monkey, Rhesus Monkey
sequence length :
297
specificity :
Clone L26, a mouse anti human CD20 antibody, recognizes the human CD20 cell surface antigen, a 33-37 kDa non-glycosylated phosphoprotein. The CD20 antigen is expressed during pre-B-cell development. It is present on both resting and activated B-cells but is lost prior to terminal B-cell differentiation into plasma cells. Clone L26 recognizes a cytoplasmic epitope of CD20.
form :
Concentrate. Tissue Culture Supernatant - liquid
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Immunohistology Paraffin
app notes :
Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Immunohistology - Frozen: Minimum Dilution: 1/10; Maximum Dilution: 1/40. Immunohistology - Paraffin: Minimum Dilution: 1/10; Maximum Dilution: 1/40
other info1 :
Perservative Stabilisers: 0.1% Sodium Azide. 1% Bovine Serum Albumin
other info2 :
Immunogen: Human tonsillar B-cells. Histology Positive Control Tissue: Human Tonsil. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Clone L26, a mouse anti human CD20 antibody, recognizes the human CD20 cell surface antigen, a 33-37 kDa non-glycosylated phosphoprotein. The CD20 antigen is expressed during pre-B-cell development. It is present on both resting and activated B-cells but is lost prior to terminal B-cell differentiation into plasma cells. Clone L26 recognizes a cytoplasmic epitope of CD20.
ncbi gi num :
23110987
ncbi acc num :
NP_068769.2
ncbi gb acc num :
NM_021950.3
uniprot acc num :
P11836
ncbi mol weight :
14,581 Da
ncbi pathways :
Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489)
ncbi summary :
This gene encodes a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein. [provided by RefSeq, Jul 2008]
uniprot summary :
MS4A1: This protein may be involved in the regulation of B-cell activation and proliferation. Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5); also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. Belongs to the MS4A family. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell surface. Chromosomal Location of Human Ortholog: 11q12. Cellular Component: extracellular space; integral to plasma membrane; external side of plasma membrane. Molecular Function: epidermal growth factor receptor binding. Biological Process: B cell proliferation; humoral immune response. Disease: Immunodeficiency, Common Variable, 5
size1 :
1 mL
price1 :
485 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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