catalog number :
MBS210546
products full name :
MOUSE ANTI HUMAN ACTIN (MUSCLE)
products short name :
ACTIN
other names :
actin, gamma-enteric smooth muscle isoform 2; Actin, gamma-enteric smooth muscle; actin, gamma-enteric smooth muscle; actin-like protein; alpha-actin-3; actin, gamma 2, smooth muscle, enteric; Alpha-actin-3; Gamma-2-actin; Smooth muscle gamma-actin
products gene name :
ACTIN
other gene names :
ACTG2; ACTG2; ACT; ACTE; VSCM; ACTA3; ACTL3; ACTSG; ACTA3; ACTL3; ACTSG
uniprot entry name :
ACTH_HUMAN
reactivity :
Cat, Chicken, Dog, Japanese Macaque, Macaque, Mouse, Rabbit, Rat, Shrew
form :
Concentrate. Tissue Culture Supernatant - liquid
storage stability :
Store at 4 degree C or at -20 degree C if prefered. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, Immunohistology Paraffin
app notes :
Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections.This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Immunohistology - Paraffin: Minimum Dilution: 1/10; Maximum Dilution: 1/40
other info1 :
Perservative Stabilisers: 0.1% Sodium Azide (NaN3). 1% Bovine Serum Albumin
other info2 :
Immunogen: Muscle actin, purified from human myocardium. Histology Positive Control Tissue: Skeletal tissue. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human actin (muscle) antibody, clone HHF35, recognizes muscle specific actin, a 42kDa protein specific for actin present in skeletal, cardiac and smooth muscle. Mouse anti Human actin (muscle) antibody, (HHF35) recognizes alpha actin and does not recognize beta actin. Mouse anti Human actin (muscle) antibody, clone HHF35 may be useful in the study of tumors such as rhabdomyosarcomas, leiomyomas and leiomyosarcomas, arising from muscle cells. Mouse anti Human actin (muscle) antibody, clone HHF35 is reported to be suitable for use in Western blotting (Tsukada et al. 1987).
ncbi acc num :
NP_001186822.1
ncbi gb acc num :
NM_001199893.1
ncbi mol weight :
37,083 Da
ncbi pathways :
Muscle Contraction Pathway 106261!!Smooth Muscle Contraction Pathway 161025!!Vascular Smooth Muscle Contraction Pathway 96530!!Vascular Smooth Muscle Contraction Pathway 96866
ncbi summary :
Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.[provided by RefSeq, Dec 2010]