This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
RAT ANTI MOUSE CD49b:Biotin
catalog :
MBS210402
quantity :
0.1 mg
price :
365 USD
clonality :
monoclonal
host :
rat
conjugate :
biotin
clone name :
DX5
reactivity :
mouse
application :
flow cytometry, FACS
product information
catalog number :
MBS210402
products type :
Antibody
products full name :
RAT ANTI MOUSE CD49b:Biotin
products short name :
CD49b
other names :
integrin alpha-2; Integrin alpha-2; integrin alpha-2; CD49 antigen-like family member B; GPIa; VLA-2 receptor, alpha 2 subunit; VLA-2 subunit alpha; collagen receptor; platelet membrane glycoprotein Ia; integrin alpha 2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD_antigen: CD49b
products gene name :
CD49b
other gene names :
Itga2; Itga2; DX5; CD49B; GPIa
uniprot entry name :
ITA2_MOUSE
clonality :
Monoclonal
isotype :
IgM
clone :
DX5
host :
Rat
sequence length :
1178
form :
Biotin. Purified IgM conjugated to Biotin - liquid
concentration :
IgM concentration 0.1 mg/ml
storage stability :
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Flow cytometry (FC/FACS)
app notes :
Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. This may be reduced by using SeroBlock FcR.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Mouse
products description :
Rat anti Mouse CD49b monoclonal antibody, clone DX5 recognizes mouse CD49b, also known as Very Late Antigen-2 (VLA-2) or alpha-2 integrin. CD49b is a ~160kDa single pass type I membrane protein expressed by NK cells and a small subset of T-cells (Pellicci et al. 2005). Rat anti mouse CD49b, clone DX5 stains NK cells from all mouse strains tested including Balb/c mice (Arese et al. 2001). CD49b acts as a receptor for collagen, laminin, fibronectin and E-cadherin (Carafoli et al. 2013).
ncbi gi num :
41054731
ncbi acc num :
NP_032422.2
ncbi gb acc num :
NM_008396.2
uniprot acc num :
Q62469
ncbi mol weight :
128,955 Da
ncbi pathways :
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 117303!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway 116129!!Axon Guidance Pathway 1111058!!CHL1 Interactions Pathway 1111082!!Developmental Biology Pathway 1111057!!Dilated Cardiomyopathy Pathway 121495!!Dilated Cardiomyopathy Pathway 121285!!ECM Proteoglycans Pathway 1110314!!ECM-receptor Interaction Pathway 83265!!ECM-receptor Interaction Pathway 479
size :
0.1 mg
price :
365 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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