This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN MAdCAM-1:Preservative Free
catalog :
MBS210208
quantity :
0.1 mg
price :
440 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
CA 102.2C1
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
product information
catalog number :
MBS210208
products type :
Antibody
products full name :
MOUSE ANTI HUMAN MAdCAM-1:Preservative Free
products short name :
MAdCAM-1
other names :
mucosal addressin cell adhesion molecule 1 isoform a; Mucosal addressin cell adhesion molecule 1; mucosal addressin cell adhesion molecule 1; MAdCAM-1; hMAdCAM-1; mucosal addressin cell adhesion molecule-1; mucosal vascular addressin cell adhesion molecule 1
products gene name :
MAdCAM-1
other gene names :
MADCAM1; MADCAM1; MACAM1; MAdCAM-1; hMAdCAM-1
uniprot entry name :
MADCA_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
CA 102.2C1
host :
Mouse
sequence length :
382
specificity :
This item recognises human MAdCAM-1 (mucosal addressin cell adhesion molecule -1), a 40kD protein expressed by vascular endothelium. Clone CA102.2C1 has been reported to block the binding of human cells expressing alpha4 Beta7 to immobilized MAdCAM-1 in vitro.
form :
Preservative Free. Purified IgG - liquid
concentration :
IgG concentration 1.0 mg/ml
storage stability :
Store at -20o only. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the product. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Functional Assays (FN), Western Blot (WB)
other info1 :
Preparation: Purified IgG prepared by affinity chromatography on Protein A
other info2 :
Immunogen: Bacterially expressed human MAdCAM-1. Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Mouse anti Human MAdCAM-1 antibody, clone CA102.2C1 recognizes human mucosal addressin cell adhesion molecule -1, also known as MAdCAM-1. Human MAdCAM-1 is a 382 amino acid ~40-60 kDa single pass type 1 transmembrane glycoprotein expressed by vascular endothelium (http://www.uniprot.org/uniprot/Q13477). Mouse anti Human MAdCAM-1 antibody, clone CA102.2C1 has been reported to block the binding of human cells expressing alpha4 Beta7 to immobilized MAdCAM-1 in vitro (Grant et al. 2001).
ncbi gi num :
109633022
ncbi acc num :
NP_570116.2
ncbi gb acc num :
NM_130760.2
uniprot acc num :
Q13477
ncbi mol weight :
21,247 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Extracellular Matrix Organization Pathway 576262!!Immune System Pathway 106386!!Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway 106413!!Integrin Cell Surface Interactions Pathway 106110!!Intestinal Immune Network For IgA Production Pathway 128760!!Intestinal Immune Network For IgA Production Pathway 128670!!Paxillin-independent Events Mediated By A4b1 And A4b7 Pathway 137971
ncbi summary :
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
440 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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