catalog number :
MBS210097
products full name :
MOUSE ANTI HUMAN IgG (CH3 DOMAIN)
products short name :
IgG
other names :
Ig gamma-3 chain C region; Ig gamma-3 chain C region; immunoglobulin heavy constant gamma 3 (G3m marker); HDC; Heavy chain disease protein
other gene names :
IGHG3; IGHG3; IgG3
uniprot entry name :
IGHG3_HUMAN
form :
Purified. Purified IgM - liquid
concentration :
Ig concentration 1 mg/ml
storage stability :
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen, ELISA (EIA), Haemagglutination (H), Immunohistology Paraffin, Western Blot (WB)
app notes :
Immunohistology: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide
other info2 :
Target Species: Human
products description :
Mouse anti Human IgG (CH3 Domain) antibody, clone A57H reacts with the CH3 domain of human IgG
ncbi mol weight :
41,287 Da
ncbi pathways :
Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); FCGR Activation Pathway (771578); Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (771577); IL4-mediated Signaling Events Pathway (137933); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Regulation Of Actin Dynamics For Phagocytic Cup Formation Pathway (771579)
uniprot summary :
IGHG3: Dimer linked by 12 disulfide bonds; it has an extra interchain disulfide bond at position 7 in addition to the 11 normally present in the hinge region. Chromosomal Location of Human Ortholog: 14q32.33. Cellular Component: extracellular space; extracellular region. Molecular Function: antigen binding. Biological Process: retinal homeostasis; innate immune response; complement activation, classical pathway; complement activation