catalog number :
MBS210053
products full name :
MOUSE ANTI HUMAN LAMININ ALPHA 5
products short name :
LAMININ
other names :
laminin subunit alpha-5; Laminin subunit alpha-5; laminin subunit alpha-5; laminin alpha-5 chain; laminin-10 subunit alpha; laminin-11 subunit alpha; laminin-15 subunit alpha; laminin, alpha 5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha
products gene name :
LAMININ ALPHA 5
other gene names :
LAMA5; LAMA5; KIAA0533; KIAA1907
uniprot entry name :
LAMA5_HUMAN
specificity :
This item reacts with the globular domain of the alpha-5 chain of intact laminin, a component of the extracellular matrix involved in cellular attachment.
storage stability :
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
tested application :
ELISA (EIA), Immunofluorescence (IF), Immunoprecipitation (IP)
other info1 :
Perservative Stabilisers: 0.09% Sodium Azide (NaN3)
other info2 :
Immunogen: Purified human laminin. Target Species: Human
products description :
MBS210053 reacts with the globular domain of the alpha-5 chain of intact laminin, a component of the extracellular matrix involved in cellular attachment.
ncbi acc num :
NP_005551.3
ncbi gb acc num :
NM_005560.4
ncbi mol weight :
61,287 Da
ncbi pathways :
Alpha6-Beta4 Integrin Signaling Pathway 198807!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Degradation Of The Extracellular Matrix Pathway 576263!!ECM Proteoglycans Pathway 833812!!ECM-receptor Interaction Pathway 83068!!ECM-receptor Interaction Pathway 479!!Extracellular Matrix Organization Pathway 576262!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067
ncbi summary :
This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013]