catalog number :
MBS210035
products full name :
MOUSE ANTI RAT CHOLINE ACETYLTRANSFERASE
products short name :
CHOLINE ACETYLTRANSFERASE
other names :
Choline O-acetyltransferase; Choline O-acetyltransferase; choline O-acetyltransferase; CHOACTase; choline acetylase; choline acetyltransferase; choline O-acetyltransferase
other gene names :
Chat; Chat; CHOACTase; ChAT; Choline acetylase
uniprot entry name :
CLAT_RAT
specificity :
This item is specific for choline acetyltransferase and stains cholinergic neurons in the brain and central nervous system. Choline acetyltransferase is an enzyme, present the presynaptic ends of axons, that catalyzes the transfer of the acetyl group of acetyl CoA to choline, forming the neurotransmitter acetylcholine.
storage stability :
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Shelf Life: 18 months from date of despatch.
tested application :
Immunohistology Frozen
app notes :
Immunohistology - Frozen: Minimum Dilution: 1/100; Maximum Dilution: 1/250
other info2 :
Immunogen: Choline acetyltransferase purified from rat brain. Target Species: Rat
products description :
MBS210035 is specific for choline acetyltransferase and stains cholinergic neurons in the brain and central nervous system.Choline acetyltransferase is an enzyme, present the presynaptic ends of axons, that catalyzes the transfer of the acetyl group of acetyl CoA to choline, forming the neurotransmitter acetylcholine.
ncbi mol weight :
71,864 Da
ncbi pathways :
Acetylcholine Neurotransmitter Release Cycle Pathway (1121163); Biogenic Amine Synthesis Pathway (198489); Cholinergic Synapse Pathway (217713); Glycerophospholipid Biosynthesis Pathway (1120984); Glycerophospholipid Metabolism Pathway (83381); Glycerophospholipid Metabolism Pathway (364); Metabolism Pathway (1120894); Metabolism Of Lipids And Lipoproteins Pathway (1120931); Neuronal System Pathway (1121153); Neurotransmitter Release Cycle Pathway (1121158)
uniprot summary :
CHAT: Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. Protein type: Lipid Metabolism - glycerophospholipid; EC 2.3.1.6; Acetyltransferase. Cellular Component: neuron projection; cell soma; mitochondrion; axon; cytoplasm. Molecular Function: choline binding; choline O-acetyltransferase activity. Biological Process: response to drug; muscle development; rhythmic excitation; metabolic process; antral ovarian follicle growth; adult walking behavior; memory; neuron differentiation; synaptic transmission; rhythmic behavior; response to ethanol; acetylcholine biosynthetic process; response to hypoxia; dendrite development; neuromuscular synaptic transmission; establishment of synaptic specificity at neuromuscular junction; response to nutrient; neurotransmitter biosynthetic process