MOUSE ANTI HUMAN CD45:APC | MyBioSource MBS210029 product information

product summary

request information :

company name :

MyBioSource

product type :

antibody

product name :

MOUSE ANTI HUMAN CD45:APC

catalog :

MBS210029

quantity :

100 Tests

price :

440 USD

clonality :

monoclonal

host :

mouse

conjugate :

APC

reactivity :

human

application :

FACS, flow cytometry

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS210029

products type :

Antibody

products full name :

MOUSE ANTI HUMAN CD45:APC

products short name :

CD45

other names :

receptor-type tyrosine-protein phosphatase C isoform 1; Receptor-type tyrosine-protein phosphatase C; receptor-type tyrosine-protein phosphatase C; CD45 antigen; T200 glycoprotein; T200 leukocyte common antigen; protein tyrosine phosphatase, receptor type, c polypeptide; protein tyrosine phosphatase, receptor type, C; Leukocyte common antigen; L-CA; T200; CD_antigen: CD45

products gene name :

CD45

other gene names :

PTPRC; PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; CD45; L-CA

uniprot entry name :

PTPRC_HUMAN

clonality :

Monoclonal

isotype :

IgG2a

clone :

F10-89-4

host :

Mouse

sequence length :

1306

form :

APC. Purified IgG conjugated to Allophycocyanin (APC) - lyophilised

storage stability :

Prior to reconstitution store at 4 degree C. Following reconstitution store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.

tested application :

Flow cytometry (FC/FACS)

app notes :

Flow Cytometry: Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood . Flow Cytometry: Maximum Dilution: Neat

other info1 :

Reconstitution: Reconstitute with 1 ml distilled water. Perservative Stabilisers: 0.09% Sodium Azide. 1% Bovine Serum Albumin. 5% Sucrose. Preparation: Purified IgG prepared by affinity chromatography from tissue culture supernatant

other info2 :

Immunogen: Human T lymphocytes. Fusion Partners: Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line. Buffer Solution: Phosphate buffered saline. Target Species: Human

products description :

Mouse anti Human CD45 antibody, clone F10-89-4 recognizes the human CD45 cell surface antigen, also known as the leucocyte common antigen (LCA). CD45 is a complex molecule existing in a number of isoforms. Antibodies recognising a common epitope on all of these isoforms are termed CD45 whilst those recognising only individual isoforms are termed CD45RA or CD45RO etc. Mouse anti Human CD45 antibody, clone F10-89-4 reacts with all forms of CD45 expressed by all haematopoietic cells, except erythrocytes, having a higher level of expression on lymphocytes than on granulocytes. Mouse anti Human CD45 antibody, clone F10-89-4 is routinely tested in flow cytometry on human peripheral blood leucocytes

ncbi gi num :

392307007

ncbi acc num :

NP_002829.3

ncbi gb acc num :

NM_002838.4

uniprot acc num :

P08575

ncbi mol weight :

130,898 Da

ncbi pathways :

Adaptive Immune System Pathway 366160!!Axon Guidance Pathway 105688!!B Cell Receptor Signaling Pathway 198909!!BCR Signaling Pathway 138058!!CXCR4-mediated Signaling Events Pathway 137910!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Developmental Biology Pathway 477129!!EPO Receptor Signaling Pathway 198882!!Fc Gamma R-mediated Phagocytosis Pathway 114228

ncbi summary :

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]

size :

100 Tests

price :

440 USD

more info or order :

MyBioSource product webpage