product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
MOUSE ANTI HUMAN FACTOR VIII:Alk. Phos.
catalog :
MBS210004
quantity :
1 ml
price :
830 USD
clonality :
monoclonal
host :
mouse
conjugate :
AP
reactivity :
human
application :
western blot, enzyme immunoassay, ELISA
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS210004
products type :
Antibody
products full name :
MOUSE ANTI HUMAN FACTOR VIII:Alk. Phos.
products short name :
FACTOR VIII
other names :
coagulation factor VIII isoform a; Coagulation factor VIII; coagulation factor VIII; antihemophilic factor; coagulation factor VIIIc; factor VIII F8B; coagulation factor VIII, procoagulant component; Antihemophilic factor; AHF; Procoagulant componentCleaved into the following 4 chains:Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain
other gene names :
F8; F8; AHF; F8B; F8C; HEMA; FVIII; DXS1253E; F8C; AHF
uniprot entry name :
FA8_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
RFF-VIIIC/8
host :
Mouse
sequence length :
2351
specificity :
Clone RFFVIIIC/8 recognises the 360kDa band of human Factor VIII as well as the 210kDa and a 92kDa band. There is no cross reactivity with Von Willebrand Factor.
form :
Alk. Phos. Purified IgG conjugated to Alkaline Phosphatase - liquid
storage stability :
Store at 4 degree C. DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
ELISA: Minimum Dilution: 1/500; Maximum Dilution: 1/2000;. Western Blotting: Minimum Dilution: 1/10; Maximum Dilution: 1/100
other info1 :
Perservative Stabilisers: 0.01% Sodium Azide (NaN3). 50% Glycerol. 1mM Magnesium Chloride. 1mM Zinc Chloride
other info2 :
Buffer Solution: Phosphate buffered saline. Target Species: Human
products description :
Clone RFFVIIIC/8 recognises the 360kDa band of human Factor VIII as well as the 210kDa and a 92kDa band. There is no cross reactivity with Von Willebrand Factor.
ncbi gi num :
4503647
ncbi acc num :
NP_000123.1
ncbi gb acc num :
NM_000132.3
uniprot acc num :
P00451
ncbi mol weight :
24,641 Da
ncbi pathways :
Blood Clotting Cascade Pathway 198840!!Common Pathway 106060!!Complement And Coagulation Cascades Pathway 198880!!Complement And Coagulation Cascades Pathway 83073!!Complement And Coagulation Cascades Pathway 484!!Formation Of Fibrin Clot (Clotting Cascade) Pathway 106057!!Hemostasis Pathway 106028!!Intrinsic Pathway 106059!!Platelet Activation, Signaling And Aggregation Pathway 106034!!Platelet Degranulation Pathway 106050
ncbi summary :
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
size :
1 ml
price :
830 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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