catalog number :
MBS2097595
products type :
Recombinant Protein
products full name :
Recombinant Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2)
products short name :
[Short Palate, Lung And Nasal Epithelium Carcinoma Associated Protein 2 (SPLUNC2)]
products name syn :
[BPIFA2; PSP; C20orf70; BPI fold-containing family A member 2; Parotid secretory protein]
other names :
[BPI fold-containing family A member 2; BPI fold-containing family A member 2; BPI fold-containing family A member 2; BPI fold containing family A member 2; Parotid secretory protein; PSP; Short palate, lung and nasal epithelium carcinoma-associated protein 2]
products gene name :
[SPLUNC2]
other gene names :
[BPIFA2; BPIFA2; PSP; SPLUNC2; C20orf70; bA49G10.1; C20orf70; SPLUNC2; PSP]
concentration :
Original Concentration: 50 ug/mL
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the
expiration date under appropriate storage condition.
tested application :
Positive Control; Immunogen; SDS-PAGE; WB. (May be suitable for use in other assays to be determined by the end user.)
image1 heading :
SDS-Page
other info1 :
Organism Species: Homo sapiens (Human). Source: Eukaryotic expression. Residues: Glu19~Ile249. Tags: N-terminal His Tag. Subcellular Location: Secreted. Traits: Freeze-dried powder. Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and
Proclin300.
other info2 :
Predicted isoelectric point: 5.2. Predicted Molecular Mass: 26.6KDa. Accurate Molecular Mass: 35kDa as determined by SDS-PAGE reducing conditions. Phenomenon explanation: The possible reasons that the actual band size differs from the predicted are as follows:. 1.Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form. 5. Polymerization of the target protein: Dimerization, multimerization etc. Usage: Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
products categories :
Signal transduction
ncbi acc num :
NP_001306093.1
ncbi gb acc num :
NM_001319164.1
ncbi pathways :
Antimicrobial Peptides Pathway (1457777); Immune System Pathway (1269170); Innate Immune System Pathway (1269203)
ncbi summary :
This gene encodes a member of the palate, lung and nasal epithelium clone (Plunc) family of proteins. Members of this family have been proposed to play a role in the local antibacterial response in nose, mouth and upper respiratory pathways. The encoded soluble salivary protein binds bacterial lipopolysaccharide (LPS) and inhibits bacterial growth. This gene is present in a gene cluster on chromosome 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
uniprot summary :
PSP: Belongs to the BPI/LBP/Plunc superfamily. Plunc family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 20q11.21. Cellular Component: extracellular region. Molecular Function: lipopolysaccharide binding; protein binding. Biological Process: antimicrobial humoral response; defense response to bacterium