Recombinant Matrix Metalloproteinase 25 (MMP25) | MyBioSource MBS2097526 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Matrix Metalloproteinase 25 (MMP25)

catalog :

MBS2097526

quantity :

0.01 mg

price :

135 USD

more info or order :

MyBioSource product webpage

image

image 1 :

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product information

catalog number :

MBS2097526

products type :

Recombinant Protein

products full name :

Recombinant Matrix Metalloproteinase 25 (MMP25)

products short name :

[Matrix Metalloproteinase 25 (MMP25)]

products name syn :

[MT6-MMP; MMP25; MMPL1; MT-MMP6; Matrix Metallopeptidase Like 1; Leukolysin; Membrane-type matrix metalloproteinase 6; Membrane-type-6 matrix metalloproteinase]

other names :

[matrix metalloproteinase-25 preproprotein; Matrix metalloproteinase-25; matrix metalloproteinase-25; matrix metallopeptidase 25; Leukolysin; Membrane-type matrix metalloproteinase 6; MT-MMP 6; MTMMP6; Membrane-type-6 matrix metalloproteinase; MT6-MMP; MT6MMP]

products gene name :

[MMP25]

other gene names :

[MMP25; MMP25; MMP20; MMPL1; MMP-25; MMP20A; MT6MMP; MTMMP6; MT-MMP6; MT6-MMP; MT-MMP 6; MMP20; MMPL1; MT6MMP; MMP-25; MT-MMP 6; MTMMP6; MT6-MMP; MT6MMP]

host :

E.coli

purity :

> 95%

concentration :

Original Concentration: 200 ug/mL

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)

image1 heading :

Sequence Information

image2 heading :

SDS-Page

image3 heading :

Testing Data

other info1 :

Organism Species: Homo sapiens(Human). Source: Prokaryotic expression. Residues: Tyr108~Ile313. Tags: N-terminal His Tag. Subcellular Location: Membrane. Traits: Freeze-dried powder. Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01%skl, 5% Trehalose.

other info2 :

Predicted isoelectric point: 5.4. Predicted Molecular Mass: 26.5kDa. Accurate Molecular Mass: 27kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

products categories :

Enzyme Metabolic pathway; Tumor immunity; Infection immunity; Cardiovascular biology

ncbi gi num :

11968059

ncbi acc num :

NP_071913.1

ncbi gb acc num :

NM_022468.4

uniprot acc num :

Q9NPA2

ncbi pathways :

Activation Of Matrix Metalloproteinases Pathway (1270258); Degradation Of The Extracellular Matrix Pathway (1270257); Extracellular Matrix Organization Pathway (1270244); Immune System Pathway (1269170); Innate Immune System Pathway (1269203); Matrix Metalloproteinases Pathway (198900); Neutrophil Degranulation Pathway (1457780)

ncbi summary :

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq, Jul 2008]

uniprot summary :

MMP25: May activate progelatinase A. Belongs to the peptidase M10A family. Protein type: Activator; Cell surface; EC 3.4.24.-; Membrane protein, GPI anchor; Membrane protein, integral; Protease. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: integral component of membrane; membrane; plasma membrane; proteinaceous extracellular matrix. Molecular Function: metalloendopeptidase activity; zinc ion binding. Biological Process: hard palate development; inflammatory response; neutrophil degranulation; proteolysis

size1 :

0.01 mg

price1 :

135 USD

size2 :

0.05 mg

price2 :

250

size3 :

0.1 mg

price3 :

385

size4 :

0.2 mg

price4 :

470

size5 :

0.5 mg

price5 :

910

size6 :

1 mg

price6 :

1345

more info or order :

MyBioSource product webpage