Biotin-Linked Polyclonal Antibody to Transmembrane Protease, Serine 2 (TMPRSS2) | MyBioSource MBS2094884 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Biotin-Linked Polyclonal Antibody to Transmembrane Protease, Serine 2 (TMPRSS2)

catalog :

MBS2094884

quantity :

0.1 mg

price :

245 USD

clonality :

polyclonal

host :

rabbit

conjugate :

biotin

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS2094884

products type :

Antibody

products full name :

Biotin-Linked Polyclonal Antibody to Transmembrane Protease, Serine 2 (TMPRSS2)

products short name :

[Transmembrane Protease, Serine 2 (TMPRSS2)]

products name syn :

[PRSS10; Serine protease 10]

other names :

[transmembrane protease serine 2 isoform 2; Transmembrane protease serine 2; transmembrane protease serine 2; transmembrane protease, serine 2; Serine protease 10]

products gene name :

[TMPRSS2]

other gene names :

[TMPRSS2; TMPRSS2; PP9284; PRSS10; PRSS10]

clonality :

Polyclonal

host :

Rabbit

purity :

Antigen-specific Affinity Chromatography.

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

concentration :

0.47 mg/ml

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; IHC; ICC; IP.

app notes :

Western blotting: 0.5-2 ug/mL;1:230-940. Immunohistochemistry: 5-20 ug/mL;1:23-94. Immunocytochemistry: 5-20 ug/mL;1:23-94. Optimal working dilutions must be determined by end user.

other info1 :

Organism Species: Homo sapiens (Human). Source: Antibody labeling. Label: Biotin. Traits: Liquid. Immunogen: Recombinant TMPRSS2 (Ser284~Gly492) expressed in E.coli

ncbi gi num :

205360943

ncbi acc num :

NP_005647.3

ncbi gb acc num :

NM_005656.3

uniprot acc num :

O15393

ncbi pathways :

Coregulation Of Androgen Receptor Activity Pathway (138085); Influenza A Pathway (217173); Influenza A Pathway (217150); Regulation Of Androgen Receptor Activity Pathway (138027); Transcriptional Misregulation In Cancer Pathway (523016); Transcriptional Misregulation In Cancer Pathway (522987)

ncbi summary :

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

uniprot summary :

TMPRSS2: a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]. Protein type: EC 3.4.21.-; Membrane protein, integral; Protease. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: integral component of plasma membrane; plasma membrane. Molecular Function: protein binding; scavenger receptor activity; serine-type endopeptidase activity; serine-type peptidase activity. Biological Process: positive regulation of virion penetration into host cell; protein autoprocessing; proteolysis; receptor-mediated endocytosis

size1 :

0.1 mg

price1 :

245 USD

size2 :

0.2 mg

price2 :

370

size3 :

1 mg

price3 :

880

more info or order :

MyBioSource product webpage