protein

Recombinant N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP)

MBS2090439

0.01 mg

135 USD

Recombinant Protein

Recombinant N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP)

[N-Terminal Pro-Atrial Natriuretic Peptide (NT-ProANP)]

[ANH; ANF; PND; NPPA; CDD-ANF; Atrial Natriuretic Factor; Atrial Natriuretic Hormone; Atriopeptin; Natriuretic Peptide Precursor A; Prepronatriodilatin; Cardiodilatin-related peptide]

[Natriuretic peptides A; Natriuretic peptides A; natriuretic peptides A; natriuretic peptide A; Prepronatriodilatin]

[NT-ProANP]

[NT-Pro-ANP; N-ANP]

[Nppa; Nppa; ANF; ANP; Pnd; RATANF; ANF; ANP]

E.coli

> 95%

20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.

Original Concentration: 200ug/mL

Storage:. Avoid repeated freeze/thaw cycles. Store at 2-8ºC for one month. Aliquot and store at -80ºC for 12 months. Stability Test:. The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Positive Control; Immunogen; SDS-PAGE; Western Blot (WB)

Sequence Information

Testing Data

SDS-Page

Organism Species: Rattus norvegicus (Rat). Source: Prokaryotic expression. Residues: Asn25~Arg122 linked with LEHHHHHH. Tags: N-terminal His Tag. Subcellular Location: Secreted

Traits: Freeze-dried powder. Predicted isoelectric point: 5.2. Phenomenon explanation: The possible reasons that the actual band size differs from the predicted are as follows:. 1.Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form. 5. Polymerization of the target protein: Dimerization, multimerization etc. Usage: Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

113870

P01161.1

P01161

Predicted Molecular Mass: 12.9kDa. Accurate Molecular Mass: 17kDa as determined by SDS-PAGE reducing conditions.

peptide involved in the control of fluid volume and vascular function [RGD, Feb 2006]

NPPA: Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. Defects in NPPA are the cause of familial atrial fibrillation type 6 (ATFB6). Atrial fibrillation is a common disorder of cardiac rhythm that is hereditary in a small subgroup of patients. It is characterized by disorganized atrial electrical activity, progressive deterioration of atrial electromechanical function and ineffective pumping of blood into the ventricles. It can be associated with palpitations, syncope, thromboembolic stroke, and congestive heart failure. Belongs to the natriuretic peptide family. Protein type: Hormone; Secreted; Secreted, signal peptide

0.01 mg

135 USD

0.05 mg

250

0.1 mg

385

0.2 mg

470

0.5 mg

910

1 mg

1345