catalog number :
MBS2085949
products full name :
Monoclonal Antibody to Regenerating Islet Derived Protein 3 Gamma (REG3g)
products short name :
[Regenerating Islet Derived Protein 3 Gamma (REG3g)]
products name syn :
[REG-III; PAP1B; PAPIB; UNQ429; Pancreatitis-associated protein 1B; Regenerating islet-derived protein III-gamma]
other names :
[regenerating islet-derived protein 3-gamma isoform 1 preproprotein; Regenerating islet-derived protein 3-gamma; regenerating islet-derived protein 3-gamma; regenerating family member 3 gamma; Pancreatitis-associated protein 1B; PAP-1B]
products gene name :
[REG3g]
other gene names :
[REG3G; REG3G; PAP1B; PAPIB; PAP IB; PAP-1B; UNQ429; LPPM429; REG III; REG-III; PAP1B; REG-3-gamma; PAP-1B; PAP IB; REG III; Reg III-gamma]
purity :
Protein A + Protein G affinity chromatography
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4ºC for frequent use. Aliquot and store at -20ºC for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IP.
app notes :
Western blotting: 0.5-5 ug/mL;1:200-2000. Immunohistochemistry: 5-20 ug/mL;1:50-200. Immunocytochemistry: 5-20 ug/mL;1:50-200. Optimal working dilutions must be determined by end user
image1 heading :
Western Blot (WB)
image2 heading :
Western Blot (WB)
image3 heading :
Immunohistochemistry (IHC)
other info1 :
Organism Species: Homo sapiens (Human). Source: Monoclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant REG3g (Ser39~Asp175 (Accession # Q6UW15)) expressed in E.coli
ncbi acc num :
NP_001008388.1
ncbi gb acc num :
NM_001008387.2
ncbi summary :
This gene encodes a member of the regenerating islet-derived genes (REG)3 protein family. These proteins are secreted, C-type lectins with a carbohydrate recognition domain and N-terminal signal peptide. The protein encoded by this gene is an antimicrobial lectin with activity against Gram-positive bacteria. Alternative splicing results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Nov 2014]
uniprot summary :
REG3G: Might be a stress protein involved in the control of bacterial proliferation. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 2p12. Cellular Component: cytoplasm; extracellular region. Molecular Function: peptidoglycan binding. Biological Process: acute-phase response; antimicrobial humoral response; cytolysis in other organism; defense response to Gram-positive bacterium; MyD88-dependent toll-like receptor signaling pathway; negative regulation of keratinocyte differentiation