product summary
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company name :
MyBioSource
product type :
antibody
product name :
APC/CY7-Linked Monoclonal Antibody to Neuregulin 4 (NRG4)
catalog :
MBS2063740
quantity :
0.1 mg
price :
550 USD
clonality :
monoclonal
host :
mouse
conjugate :
APC/Cy7
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2063740
products type :
Antibody
products full name :
APC/CY7-Linked Monoclonal Antibody to Neuregulin 4 (NRG4)
products short name :
[Neuregulin 4 (NRG4)]
other names :
[Neuregulin 4; Pro-neuregulin-4, membrane-bound isoform; pro-neuregulin-4, membrane-bound isoform; neuregulin 4]
products gene name :
[NRG4]
other gene names :
[NRG4; NRG4; HRG4; Pro-NRG4; NRG-4]
clonality :
Monoclonal
host :
Mouse
purity :
Protein A/G Affinity Chromatography.
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
0.25 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
WB; IHC; ICC; IF.
app notes :
Western blotting: 0.5-2 Ug/mL;1:120-500. Immunohistochemistry: 5-20 Ug/mL;1:12-50. Immunocytochemistry: 5-20 Ug/mL;1:12-50. Optimal working dilutions must be determined by end user.
other info1 :
Organism Species: Homo sapiens (Human). Source: Monoclonal antibody preparation. Label: APC/CY7. Traits: Liquid. Immunogen: Recombinant NRG4 (Met1~Phe62) expressed in E.coli.
ncbi gi num :
17068379
ncbi acc num :
AAH17568.1
ncbi pathways :
Adaptive Immune System Pathway (366160); Constitutive PI3K/AKT Signaling In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764); Downstream Signal Transduction Pathway (106385); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream Signaling Of Activated FGFR Pathway (160957); ErbB Receptor Signaling Network Pathway (138016); ErbB Signaling Pathway (198844)
ncbi summary :
The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008]
uniprot summary :
NRG4: Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors. Belongs to the neuregulin family. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 15q24.2. Cellular Component: extracellular region; extracellular space. Molecular Function: phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; receptor binding. Biological Process: MAPKKK cascade; organ development; phosphoinositide-mediated signaling; regulation of phosphoinositide 3-kinase cascade
size1 :
0.1 mg
price1 :
550 USD
size2 :
0.2 mg
price2 :
775
size3 :
1 mg
price3 :
1885
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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