catalog number :
MBS206090
products type :
Recombinant Protein
products full name :
Lrpap1, 29-360aa, Mouse, His tag, E Coli
products short name :
[Lrpap1]
products name syn :
[Alpha-2-macroglobulin receptor-associated protein; Alpha 2 macroglobulin receptor associated protein; AA617339; AI790446; AU042172; C77774; HBP44; RAP]
other names :
[alpha-2-macroglobulin receptor-associated protein; Alpha-2-macroglobulin receptor-associated protein; alpha-2-macroglobulin receptor-associated protein; low density lipoprotein receptor-related protein associated protein 1; Heparin-binding protein 44; HBP-44; Low density lipoprotein receptor-related protein-associated protein 1; RAP]
products gene name :
[Lrpap1]
other gene names :
[Lrpap1; Lrpap1; RAP; HBP44; C77774; AA617339; AI790446; AU042172; Alpha-2-MRAP; HBP-44; RAP]
sequence length :
29-360aa
purity :
> 90% by SDS-PAGE
form :
Liquid, In Phosphate buffered saline (pH 7.4) containing 10% glycerol
concentration :
1mg/ml (determined by Absorbance at 280nm)
storage stability :
Can be stored at 2-8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
other info1 :
Tag Information: His-tag
products categories :
Metabolism
products description :
Lrpap1 also known as Alpha-2-macroglobulin receptor-associated protein. The alpha-2-macroglobulin receptor-associated protein (RAP) is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. Lrpap1 acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. Lrpap1 may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II. Recombinant mouse Lspap1, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
products references :
Strickland D.K., et al. (1991) J. Biol. Chem. 266:13364-13369. ; Van Leuven F., et al. (1998) Genomics 52:145-151.
ncbi gb acc num :
NM_013587.2
ncbi mol weight :
41.4kDa (355aa) confirmed by MALDI-TOF
uniprot summary :
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.