protein

NDuFA4, 1-81aa, Human, His tag, E Coli

MBS205754

0.1 mg

310 USD

Recombinant Protein

NDuFA4, 1-81aa, Human, His tag, E Coli

NDuFA4

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; CI-9k; CI-MLRQ; MLRQ

cytochrome c oxidase subunit NDUFA4; Cytochrome c oxidase subunit NDUFA4; cytochrome c oxidase subunit NDUFA4; Complex I 9kDa subunit; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; NADH-ubiquinone oxidoreductase MLRQ subunit; complex I-MLRQ; NDUFA4, mitochondrial complex associated; Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunit

NDuFA4

NDUFA4; NDUFA4; MLRQ; CI-9k; CI-MLRQ; CI-MLRQ

NDUA4_HUMAN

81

MGSSHHHHHH SSGLVPRGSH MGSMLRQIIG QAKKHPSLIP LFVFIGTGAT GATLYLLRLA LFNPDVCWDR NNPEPWNKLG PNDQYKFYSV NVDYSKLKKE RPDF

> 80 % by SDS - PAGE

Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

1.0 mg/ml (determined by Bradford assay)

Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.

SDS-PAGE

Antigen Species: Human. Tag: His-tag

Expression System: E Coli

Signal Transduction

NDuFA4 belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Recombinant human NDuFA4 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Kim J.W., Lee Y., et al. (1997), Biochem. Mol. Biol. Int. 43:669-675

4505357

NP_002480

NM_002489.3

11.8 kDa (104aa)

Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Electron Transport Chain Pathway (198860); Huntington's Disease Pathway (83100); Huntington's Disease Pathway (512); Metabolic Pathways (132956); Metabolism Pathway (477135); NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway (413408); NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway (890443); Non-alcoholic Fatty Liver Disease (NAFLD) Pathway (862188)

The protein encoded by this gene belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]

NDUFA4: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA4 subunit family. Protein type: EC 1.6.99.3; Mitochondrial; EC 1.6.5.3; Energy Metabolism - oxidative phosphorylation; Oxidoreductase. Chromosomal Location of Human Ortholog: 7p21.3. Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex IV; mitochondrial respiratory chain complex I. Molecular Function: protein binding; cytochrome-c oxidase activity; NADH dehydrogenase (ubiquinone) activity; protein complex binding. Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone

0.1 mg

310 USD

0.5 mg

720