product summary
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company name :
MyBioSource
product type :
antibody
product name :
APC/CY7-Linked Polyclonal Antibody to Lymphotoxin Beta (LTb)
catalog :
MBS2056549
quantity :
0.1 mg
price :
595 USD
clonality :
polyclonal
host :
rabbit
conjugate :
APC/Cy7
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2056549
products type :
Antibody
products full name :
APC/CY7-Linked Polyclonal Antibody to Lymphotoxin Beta (LTb)
products short name :
[Lymphotoxin Beta (LTb)]
products name syn :
[LT-B; p33; TNFC; TNF-C; TNFSF3; Tumor necrosis factor ligand superfamily member 3; Tumor Necrosis Factor C]
other names :
[lymphotoxin beta; Lymphotoxin-beta; lymphotoxin-beta; lymphotoxin beta; Tumor necrosis factor C; TNF-C; Tumor necrosis factor ligand superfamily member 3]
products gene name :
[LTb]
other gene names :
[LTB; LTB; p33; TNFC; TNFSF3; TNLG1C; TNFC; TNFSF3; LT-beta; TNF-C]
clonality :
Polyclonal
host :
Rabbit
purity :
Antigen-specific Affinity Chromatography.
form :
Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
concentration :
0.25 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF).
app notes :
Western blotting: 0.5-2 ug/mL;1:120-500 . Immunohistochemistry: 5-20 ug/mL;1:12-50. Immunocytochemistry: 5-20 ug/mL;1:12-50. Optimal working dilutions must be determined by end user.
other info1 :
Organism Species: Mus musculus (Mouse). Source: Antibody labeling. Label: APC/CY7. Traits: Liquid
other info2 :
Immunogen: Recombinant LTb (Ile58~Met304) expressed in E.coli.
ncbi gi num :
4337113
ncbi acc num :
AAD18089.1
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); NF-kappa B Signaling Pathway (634527); Rheumatoid Arthritis Pathway (200309); Rheumatoid Arthritis Pathway (200269); Spinal Cord Injury Pathway (739007)
ncbi summary :
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
uniprot summary :
LTB: Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 6p21.33. Cellular Component: plasma membrane. Molecular Function: receptor binding. Biological Process: cell-cell signaling; positive regulation of interleukin-12 biosynthetic process; signal transduction; tumor necrosis factor-mediated signaling pathway
size1 :
0.1 mg
price1 :
595 USD
size2 :
0.2 mg
price2 :
935
size3 :
1 mg
price3 :
2290
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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