catalog number :
MBS205576
products type :
Recombinant Protein
products full name :
MMP28,123-520aa, Human, His tag, E Coli (Denatured)
products short name :
[MMP28]
products name syn :
[Matrix metallopeptidase 28; EPILYSIN; MM28; MMP-28; MMP25]
other names :
[matrix metalloproteinase-28 isoform 1 preproprotein; Matrix metalloproteinase-28; matrix metalloproteinase-28; matrix metallopeptidase 28; Epilysin]
products gene name :
[MMP28]
other gene names :
[MMP28; MMP28; MM28; MMP25; MMP-25; MMP-28; EPILYSIN; MMP25; MMP-28]
sequence :
MGSSHHHHHH SSGLVPRGSH MGSFAKQGNK WYKQHLSYRL VNWPEHLPEP AVRGAVRAAF QLWSNVSALE FWEAPATGPA DIRLTFFQGD HNDGLGNAFD GPGGALAHAF LPRRGEAHFD QDERWSLSRR RGRNLFVVLA HEIGHTLGLT HSPAPRALMA PYYKRLGRDA LLSWDDVLAV QSLYGKPLGG SVAVQLPGKL FTDFETWDSY SPQGRRPETQ GPKYCHSSFD AITVDRQQQL YIFKGSHFWE VAADGNVSEP RPLQERWVGL PPNIEAAAVS LNDGDFYFFK GGRCWRFRGP KPVWGLPQLC RAGGLPRHPD AALFFPPLRR LILFKGARYY VLARGGLQVE PYYPRSLQDW GGIPEEVSGA LPRPDGSIIF FRDDRYWRLD QAKLQATTSG RWATELPWMG CWHANSGSAL F
purity :
> 85% by SDS-PAGE
form :
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.4M urea, 10% glycerol
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
other info1 :
Antigen Species: Human. Tag Information: His-tag
products categories :
Cancer
products description :
MMP28 protein of the matrix metalloproteinase (MMP) family is involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. MMP28 is a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Transcript variants encoding different isoforms have been described. Recombinant human MMP28 protein, fused to His-tag at N-terminus, was expressed in E Coli.
products references :
Marchenko G.N., et al. (2001) Gene. 265:87-93; Lohi J., et al. (2001) J. Biol. Chem. 276:10134-10144;
ncbi gb acc num :
NM_024302.4
ncbi mol weight :
47.3 kDa (421aa)
ncbi pathways :
Matrix Metalloproteinases Pathway (198900)
ncbi summary :
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
uniprot summary :
Can degrade casein. Could play a role in tissues homeostasis and repair.