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company name :
MyBioSource
product type :
protein
product name :
FAA,H2, 32-532aa, Human, His tag, E Coli (Denatured)
catalog :
MBS205445
quantity :
0.1 mg
price :
310 USD
more info or order :
image
image 1 :
product information
catalog number :
MBS205445
products type :
Recombinant Protein
products full name :
FAA,H2, 32-532aa, Human, His tag, E Coli (Denatured)
products short name :
[FAA,H2]
products name syn :
[Fatty-acid amide hydrolase 2; Fatty acid amide hydrolase 2; AMDD]
other names :
[fatty-acid amide hydrolase 2 isoform 1; Fatty-acid amide hydrolase 2; fatty-acid amide hydrolase 2; fatty acid amide hydrolase 2; Amidase domain-containing protein; Anandamide amidohydrolase 2; Oleamide hydrolase 2]
products gene name :
[FAAH2]
other gene names :
[FAAH2; FAAH2; AMDD; AMDD]
host :
E Coli
sequence length :
532
sequence :
MGSSHHHHHH SSGLVPRGSH MGSGGPKFAS KTPRPVTEPL LLLSGMQLAK LIRQRKVKCI DVVQAYINRI KDVNPMINGI VKYRFEEAMK EAHAVDQKLA EKQEDEATLE NKWPFLGVPL TVKEAFQLQG MPNSSGLMNR RDAIAKTDAT VVALLKGAGA IPLGITNCSE LCMWYESSNK IYGRSNNPYD LQHIVGGSSG GEGCTLAAAC SVIGVGSDIG GSIRMPAFFN GIFGHKPSPG VVPNKGQFPL AVGAQELFLC TGPMCRYAED LAPMLKVMAG PGIKRLKLDT KVHLKDLKFY WMEHDGGSFL MSKVDQDLIM TQKKVVVHLE TILGASVQHV KLKKMKYSFQ LWIAMMSAKG HDGKEPVKFV DLLGDHGKHV SPLWELIKWC LGLSVYTIPS IGLALLEEKL RYSNEKYQKF KAVEESLRKE LVDMLGDDGV FLYPSHPTVA PKHHVPLTRP FNFAYTGVFS ALGLPVTQCP LGLNAKGLPL GIQVVAGPFN DHLTLAVAQY LEKTFGGWVC PGKF
purity :
> 80% by SDS-PAGE
form :
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing, 10% glycerol, 0.4M urea
concentration :
1.0 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
products categories :
Metabolism
products description :
FAAH2 is a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate. Recombinant human FAAH2 protein, fused to His-tag at N-terminus, was expressed in E Coli.
products references :
Wei B.Q., Mikkelsen T.S. et al. (2006). J. Biol. Chem. 281:36569-36578
ncbi gi num :
195972892
ncbi acc num :
NP_777572
ncbi gb acc num :
NM_174912.3
uniprot acc num :
Q6GMR7
ncbi mol weight :
57.4kDa (524aa)
ncbi pathways :
Arachidonic Acid Metabolism Pathway (1270087); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Anandamide Degradation Pathway (142420)
ncbi summary :
This gene encodes a fatty acid amide hydrolase that shares a conserved protein motif with the amidase signature family of enzymes. The encoded enzyme is able to catalyze the hydrolysis of a broad range of bioactive lipids, including those from the three main classes of fatty acid amides; N-acylethanolamines, fatty acid primary amides and N-acyl amino acids. This enzyme has a preference for monounsaturated acyl chains as a substrate. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
uniprot summary :
Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates.
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
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