catalog number :
MBS205420
products type :
Recombinant Protein
products full name :
PLAC8, 1-115aa, Human, His tag, E Coli
products short name :
PLAC8
products name syn :
Placenta-specific 8; C15; onzin
other names :
placenta-specific gene 8 protein; Placenta-specific gene 8 protein; placenta-specific gene 8 protein; down-regulated in gastrointestinal cancer protein; placenta-specific 8; Protein C15
products gene name :
PLAC8
other gene names :
PLAC8; PLAC8; C15; DGIC; onzin
uniprot entry name :
PLAC8_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MGSMQAQAPV VVVTQPGVGP GPAPQNSNWQ TGMCDCFSDC GVCLCGTFCF PCLGCQVAAD MNECCLCGTS VAMRTLYRTR YGIPGSICDD YMATLCCPHC TLCQIKRDIN RRRAMRTF
purity :
> 85% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
concentration :
1mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Development
products description :
PLAC8 belongs to the cornifelin family. This protein is expressed at high levels in plasmacytoid dendritic cells, spleen, lymph nodes, peripheral blood leukocytes, and bone marrow. Recombinant human PLAC8 protein, fused to His-tag at N-terminus, was expressed in E.coli.
products references :
Wu S.F., et al. (2010) Leukemia. 24:544-551. Rual J.F., et al. (2005) Nature. 437:1173-1178
ncbi acc num :
NP_001124188
ncbi gb acc num :
NM_001130716.1
ncbi mol weight :
14.9 kDa (138aa)
ncbi pathways :
Gastric Cancer Network 2 Pathway (760637)
uniprot summary :
PLAC8: Belongs to the cornifelin family. Chromosomal Location of Human Ortholog: 4q21.22. Molecular Function: chromatin binding. Biological Process: negative regulation of multicellular organism growth; defense response to bacterium; positive regulation of cell proliferation; brown fat cell differentiation; positive regulation of transcription from RNA polymerase II promoter; response to cold; negative regulation of apoptosis