catalog number :
MBS205362
products type :
Recombinant Protein
products full name :
mug, 1-168aa, E Coli, His tag, E Coli
products short name :
[mug]
products name syn :
[G/u mismatch-specific DNA glycosylase; xanthine DNA glycosylase; dug; ECK3058; JW3040; ygjF]
other names :
[G/U mismatch-specific DNA glycosylase; xanthine DNA glycosylase; G/U mismatch-specific DNA glycosylase; G/U mismatch-specific DNA glycosylase; xanthine DNA glycosylase; Double-strand-specific uracil glycosylase; Mismatch-specific uracil DNA-glycosylase; MUG]
products gene name :
[mug]
other gene names :
[mug; mug; dug; ECK3058; JW3040; ygjF; ygjF; MUG]
purity :
> 90% by SDS-PAGE
form :
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 2-8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-PAGE
other info1 :
Antigen Species: E Coli,. Tag Information: His-tag
products categories :
Enzymes & Proteases
products references :
Lee HW., et al. (2010) J Biol Chem. 285 (53):41483-90; Gallinari P., et al. (1996) Nature. 383 (6602):735-8.;
ncbi gb acc num :
NC_000913.3
ncbi mol weight :
21.1 kDa (191aa) confirmed by MALDI-TOF
ncbi pathways :
Base Excision Repair Pathway (1126); Base Excision Repair Pathway (451)
ncbi summary :
Endonuclease IV stimulates Mug activity in vitro by promoting disassociation from the DNA and enzyme turnover. [More information is available at EcoGene: EG12717]. Mug is a glycosylase that acts in DNA repair . [More information is available at EcoCyc: EG12717].
uniprot summary :
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells.