catalog number :
MBS205268
products type :
Recombinant Protein
products full name :
MIEN1, 1-112aa, Human, His tag, E Coli
products short name :
[MIEN1]
products name syn :
[Migration and invasion enhancer 1; C17orf37; C35; ORB3; RDX12; XTP4]
other names :
[migration and invasion enhancer 1 isoform 1; Migration and invasion enhancer 1; migration and invasion enhancer 1; migration and invasion enhancer 1; HBV X-transactivated gene 4 protein; HBV XAg-transactivated protein 4; Protein C35]
products gene name :
[MIEN1]
other gene names :
[MIEN1; MIEN1; C35; ORB3; XTP4; RDX12; C17orf37; C17orf37; RDX12; XTP4]
sequence positions :
[1-112]
sequence :
MGSSHHHHHH SSGLVPRGSH MGSMSGEPGQ TSVAPPPEEV EPGSGVRIVV EYCEPCGFEA TYLELASAVK EQYPGIEIES RLGGTGAFEI EINGQLVFSK LENGGFPYEK DLIEAIRRAS NGETLEKITN SRPPC
purity :
> 95% by SDS-PAGE
form :
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 2 degree C to 8 degree C for short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C to -80 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag Information: His-tag
products categories :
Cancer
products description :
MIEN1 belongs to the SelWTH family. This protein Increases cell migration by inducing filopodia formation at the leading edge of migrating cells and plays a role in regulation of apoptosis, possibly through control of CASP3. It also may be involved in a redox-related process. Recombinant human MIEN1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
products references :
Dasgupta,S., et al. (2011) J. Biol. Chem. 286 (29), 25935-25946; Katz,E., et al. (2011) Anal Cell Pathol (Amst) 34 (1-2), 35-48
ncbi gb acc num :
NM_032339.4
ncbi mol weight :
14.5kDa (135aa), confirmed by MALDI-TOF
uniprot summary :
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.