catalog number :
MBS2052534
products full name :
APC-Linked Polyclonal Antibody to Granzyme K (GZMK)
products short name :
[Granzyme K (GZMK)]
products name syn :
[GZM-K; TRYP2; PRSS; Serine Protease, Granzyme 3; Tryptase II; Fragmentin-3; Granzyme-3; NK-tryptase-2]
other names :
[granzyme K; Granzyme K; granzyme K; granzyme K; Fragmentin-3; Granzyme-3; NK-tryptase-2; NK-Tryp-2]
products gene name :
[GZMK]
other gene names :
[GZMK; GZMK; TRYP2; TRYP2; NK-Tryp-2]
purity :
Antigen-specific Affinity Chromatography
form :
Supplied as solution form in 0.01M PBS, pH 7.4, containing 0.05% Proclin-300, 50% Glycerol.
concentration :
0.13 mg/mL
storage stability :
Storage: Avoid repeated freeze-thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropiate storage condition.
tested application :
WB, IHC, ICC, IF
app notes :
Western Blotting 0.5-2 ug/mL; 1:60-260. Immunohistochemistry: 5-20 ug/mL; 1:6-26. Immunocytochemistry: 5-20 ug/mL;1:6-16. Optimal working dilutions must be determined by end user.
other info1 :
Organism Species: Mus musculus (Mouse). Source: Antibody labeling. Traits: Liquid. Immunogen: Recombinant GZMK (Gln44-Val227) expressed in E.coli.
other info2 :
Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2027859
ncbi acc num :
NP_002095.1
ncbi gb acc num :
NM_002104.2
ncbi summary :
This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]
uniprot summary :
GZMK: this protein is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]. Protein type: EC 3.4.21.-; Protease; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 5q11.2. Molecular Function: serine-type peptidase activity