product summary
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company name :
MyBioSource
product type :
protein
product name :
IGJ, 23-159aa, Human, His tag, E Coli
catalog :
MBS205169
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS205169
products type :
Recombinant Protein
products full name :
IGJ, 23-159aa, Human, His tag, E Coli
products short name :
IGJ
products name syn :
Immunoglobulin J chain; IGCJ; JCH
other names :
immunoglobulin J chain; Immunoglobulin J chain; immunoglobulin J chain; IgJ chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
products gene name :
IGJ
other gene names :
IGJ; IGJ; JCH; IGCJ; IGCJ
uniprot entry name :
IGJ_HUMAN
sequence length :
159
sequence :
MGSSHHHHHH SSGLVPRGSH MGSQEDERIV LVDNKCKCAR ITSRIIRSSE DPNEDIVERN IRIIVPLNNR ENISDPTSPL RTRFVYHLSD LCKKCDPTEV ELDNQIVTAT QSNICDEDSA TETCYTYDRN KCYTAVVPLV YGGETKMVET ALTPDACYPD
purity :
> 85% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Immunology
products description :
Immunoglobulin J chain, also known as IGJ, serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also helps to bind these immunoglobulins to secretory component. Recombinant human IGJ protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Liu T., et al. (2005) J. Proteome Res. 4:2070-2080. Ramachandran P., et al. (2006) J. Proteome Res. 5:1493-1503.
ncbi gi num :
21489959
ncbi acc num :
NP_653247
ncbi gb acc num :
NM_144646.3
ncbi mol weight :
18.0 kDa (160aa) confirmed by MALDI-TOF
uniprot summary :
IGJ: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 4q21. Cellular Component: extracellular space; extracellular region. Molecular Function: peptidoglycan binding; protein homodimerization activity; IgA binding; phosphatidylcholine binding; antigen binding; single-stranded DNA binding. Biological Process: retinal homeostasis; positive regulation of protein oligomerization; adaptive immune response; glomerular filtration; antibacterial humoral response; innate immune response; immune response
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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