catalog number :
MBS205136
products type :
Recombinant Protein
products full name :
TRIP10, 260-545aa, Human, His tag, E Coli
products short name :
TRIP10
products name syn :
Cdc42-interacting protein 4; CIP4; HSTP; STOT; STP
other names :
cdc42-interacting protein 4 isoform 2; Cdc42-interacting protein 4; cdc42-interacting protein 4; TR-interacting protein 10; protein Felic; salt tolerant protein; salt tolerator; thyroid receptor-interacting protein 10; thyroid hormone receptor interactor 10; Protein Felic; Salt tolerant protein; hSTP; Thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10
products gene name :
TRIP10
other gene names :
TRIP10; TRIP10; STP; CIP4; HSTP; STOT; TRIP-10; CIP4; STOT; STP; hSTP; TR-interacting protein 10; TRIP-10
uniprot entry name :
CIP4_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MGSDPKNDSH VLIELHKSGF ARPGDVEFED FSQPMNRAPS DSSLGTPSDG RPELRGPGRS RTKRWPFGKK NKTVVTEDFS HLPPEQQRKR LQQQLEERSR ELQKEVDQRE ALKKMKDVYE KTPQMGDPAS LEPQIAETLS NIERLKLEVQ KYEAWLAEAE SRVLSNRGDS LSRHARPPDP PASAPPDSSS NSASQDTKES SEEPPSEESQ DTPIYTEFDE DFEEEPTSPI GHCVAIYHFE GSSEGTISMA EGEDLSLMEE DKGDGWTRVR RKEGGEGYVP TSYLRVTLN
purity :
> 90% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Cancer
products description :
Cdc42-interacting protein 4, also known as TRIP10, belongs to the F-BAR family of proteins. These proteins contain an N-terminal, alpha-helical, region that is hydrophobic and considered to be related to the Bin Amphiphysin Rvs (BAR) protein family. Expressed in a variety of tissues, including kidney, brain, liver, lung, heart and pancreas, TRIP10 is required for the Insulin-dependent translocation of Glut4 to the plasma membrane and is essential for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Recombinant human TRIP10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Aspenstrom P., et al. (1997) Curr Biol. 7: 479-487. Holbert S., et al. (2003) Proc Natl Acad Sci uSA. 100: 2712-2717.
ncbi gb acc num :
NM_004240.3
ncbi mol weight :
34.6kDa (309aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
ncbi pathways :
Insulin Pathway 138026!!Insulin Signaling Pathway 83090!!Insulin Signaling Pathway 501!!Insulin-mediated Glucose Transport Pathway 137981!!Rho GTPase Cycle Pathway 106503!!Signal Transduction Pathway 477114!!Signaling By Rho GTPases Pathway 106502