product summary
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company name :
MyBioSource
product type :
protein
product name :
TNFRSF6B, 30-300aa, Human, His tag, E Coli (Denatured)
catalog :
MBS204874
quantity :
0.1 mg
price :
310 USD
more info or order :
image
image 1 :
product information
catalog number :
MBS204874
products type :
Recombinant Protein
products full name :
TNFRSF6B, 30-300aa, Human, His tag, E Coli (Denatured)
products short name :
[TNFRSF6B]
products name syn :
[Tumor necrosis factor receptor superfamily member 6B; Tumor necrosis factor receptor superfamily member 6B; DCR3; DJ583P15.1.1; Decoy receptor 3; Decoy receptor for Fas ligand; M68; TR6]
other names :
[tumor necrosis factor receptor superfamily member 6B; Tumor necrosis factor receptor superfamily member 6B; tumor necrosis factor receptor superfamily member 6B; TNF receptor superfamily member 6b; Decoy receptor 3; DcR3; Decoy receptor for Fas ligand; M68]
products gene name :
[TNFRSF6B]
other gene names :
[TNFRSF6B; TNFRSF6B; M68; TR6; DCR3; M68E; DJ583P15.1.1; DCR3; TR6; DcR3]
host :
E Coli
sequence length :
300
sequence :
MGSSHHHHHH SSGLVPRGSH MGSVAETPTY PWRDAETGER LVCAQCPPGT FVQRPCRRDS PTTCGPCPPR HYTQFWNYLE RCRYCNVLCG EREEEARACH ATHNRACRCR TGFFAHAGFC LEHASCPPGA GVIAPGTPSQ NTQCQPCPPG TFSASSSSSE QCQPHRNCTA LGLALNVPGS SSHDTLCTSC TGFPLSTRVP GAEECERAVI DFVAFQDISI KRLQRLLQAL EAPEGWGPTP RAGRAALQLK LRRRLTELLG AQDGALLVRL LQALRVARMP GLERSVRERF LPVH
purity :
> 85% by SDS-PAGE
form :
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 10% glycerol 0.4M urea
concentration :
1mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
other info1 :
Antigen Species: Human. Tag Information: His-tag
products categories :
Immunology
products description :
TNFRSF6B belongs to Tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. This protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Recombinant human TNFRSF6B protein, fused to His-tag at N-terminus, was expressed in E Coli.
products references :
Pitti RM. et al. (1999) Nature. 396 : 699-703. ; Yu KY. et al. (1999) J Biol Chem. 274: 13733-13736;
ncbi gi num :
4507585
ncbi acc num :
NP_003814
ncbi gb acc num :
NM_003823.3
uniprot acc num :
O95407
ncbi mol weight :
32.1 kDa (294aa)
ncbi pathways :
Apoptosis Modulation And Signaling Pathway (198822); Cytokine Signaling In Immune System Pathway (1269310); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Immune System Pathway (1269170); TNFR2 Non-canonical NF-kB Pathway (1269329); TNFs Bind Their Physiological Receptors Pathway (1269332)
ncbi summary :
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript. [provided by RefSeq, Feb 2011]
uniprot summary :
Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis.
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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