catalog number :
MBS204842
products type :
Recombinant Protein
products full name :
FAM84A, 1-292aa, Human, His tag, E Coli
products short name :
FAM84A
products name syn :
protein FAM84A; NSE1; PP11517
other names :
protein FAM84A; Protein FAM84A; protein FAM84A; neurologic sensory protein 1; neurological/sensory 1; family with sequence similarity 84, member A; Neurologic sensory protein 1; NSE1
products gene name :
FAM84A
other gene names :
FAM84A; FAM84A; NSE1; PP11517; NSE1; NSE1
uniprot entry name :
FA84A_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MGSMGNQLDR ITHLNYSELP TGDPSGIEKD ELRVGVAYFF SDDEEDLDER GQPDKFGVKA PPGCTPCPES PSRHHHHLLH QLVLNETQFS AFRGQECIFS KVSGGPQGAD LSVYAVTALP ALCEPGDLLE LLWLQPAPEP PAPAPHWAVY VGGGQIIHLH QGEIRQDSLY EAGAANVGRV VNSWYRYRPL VAELVVQNAC GHLGLKSEEI CWTNSESFAA WCRFGKREFK AGGEVPAGTQ PPQQQYYLKV HLGENKVHTA RFHSLEDLIR EKRRIDASGR LRVLQELADL VDDKE
purity :
> 90% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
concentration :
1.0 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products description :
FAM84A belongs to the FAM84 family of proteins and is predominantly expressed in testis. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. FAM84A is up-regulated in colorectal cancer lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells. Recombinant human FAM84A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Kobayashi,T., et al. (2006) Int. J. Oncol. 29 (2), 341-347
ncbi gb acc num :
NM_145175.2
ncbi mol weight :
34.9kDa (315aa), confirmed by MALDI-TOF
uniprot summary :
FAM84A: Belongs to the FAM84 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 2p24.3