catalog number :
MBS204813
products type :
Recombinant Protein
products full name :
CALML3, 1-149aa, Human, His tag, E Coli
products short name :
CALML3
products name syn :
Calmodulin-like protein 3; CLP
other names :
calmodulin-like protein 3; Calmodulin-like protein 3; calmodulin-like protein 3; caM-like protein; calmodulin-related protein NB-1; calmodulin-like 3; CaM-like protein; CLP; Calmodulin-related protein NB-1
products gene name :
CALML3
other gene names :
CALML3; CALML3; CLP; CLP
uniprot entry name :
CALL3_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MGSHMADQLT EEQVTEFKEA FSLFDKDGDG CITTRELGTV MRSLGQNPTE AELRDMMSEI DRDGNGTVDF PEFLGMMARK MKDTDNEEEI REAFRVFDKD GNGFVSAAEL RHVMTRLGEK LSDEEVDEMI RAADTDGDGQ VNYEEFVRVL VSK
purity :
> 90% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol.
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Signal Transduction
products description :
CALML3 belongs to the calmodulin family and contains 4 EF-hand domains. This protein may be similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinities, to cellular substrates. CALML3 is expressed in normal mammary, prostate, cervical, and epidermal tissues. Recombinant human CALML3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Rual JF, Venkatesan K, et al. (2005). Nature. 437(7062):1173-8. Bennett RD, Mauer AS, et al. (2007). J Biol Chem. 282(5):3205-12.
ncbi gb acc num :
NM_005185.3
ncbi mol weight :
19 kDa (173aa), confirmed by MALDI-TOF
ncbi pathways :
Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Alcoholism Pathway (585563); Alcoholism Pathway (587116); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Amphetamine Addiction Pathway (547607); Amphetamine Addiction Pathway (550546); Calcium Signaling Pathway (83050)
uniprot summary :
CALML3: May be similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinities, to cellular substrates. Belongs to the calmodulin family. Protein type: Calcium-binding. Chromosomal Location of Human Ortholog: 10p15.1. Molecular Function: protein binding; calcium ion binding