product summary
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company name :
MyBioSource
product type :
protein
product name :
coaA, 1-316aa, E Coli, His tag, E Coli
catalog :
MBS204761
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS204761
products type :
Recombinant Protein
products full name :
coaA, 1-316aa, E Coli, His tag, E Coli
products short name :
coaA
products name syn :
pantothenate kinase; panK; rts; ts-9
other names :
pantothenate kinase; Pantothenate kinase; pantothenate kinase; Pantothenic acid kinase; Rts protein
products gene name :
coaA
other gene names :
coaA; coaA; ECK3966; JW3942; panK; rts; ts-9; panK; rts
uniprot entry name :
COAA_ECOLI
sequence length :
316
sequence :
MGSSHHHHHH SSGLVPRGSH MGSHMSIKEQ TLMTPYLQFD RNQWAALRDS VPMTLSEDEI ARLKGINEDL SLEEVAEIYL PLSRLLNFYI SSNLRRQAVL EQFLGTNGQR IPYIISIAGS VAVGKSTTAR VLQALLSRWP EHRRVELITT DGFLHPNQVL KERGLMKKKG FPESYDMHRL VKFVSDLKSG VPNVTAPVYS HLIYDVIPDG DKTVVQPDIL ILEGLNVLQS GMDYPHDPHH VFVSDFVDFS IYVDAPEDLL QTWYINRFLK FREGAFTDPD SYFHNYAKLT KEEAIKTAMT LWKEINWLNL KQNILPTRER ASLILTKSAN HAVEEVRLRK
purity :
> 95% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
concentration :
1mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: E Coli. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Metabolism
products description :
coaA (pantothenate kinase) belongs to the prokaryotic pantothenate kinase family. Pantothenate kinase (PanK; CoaA) is the first enzyme in the Coenzyme A biosynthetic pathway. It phophorylates pantothenate (vitamin B5) to form 4'-phosphopantothenate. Regulation of pantothenate kinase activity by feedback inhibition is the critical factor controlling the intracellular CoA concentration. Recombinant E.coli coaA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Song W.-J., et al. (1992) J.Bacteriol. 174:6411-6417. Song W.-J., et al. (1992) J.Bacteriol. 174:1705-1706
ncbi gi num :
16131808
ncbi acc num :
NP_418405
ncbi gb acc num :
NC_000913.3
uniprot acc num :
P0A6I3
ncbi mol weight :
38.9kDa (340aa), confirmed by MALDI-TOF
ncbi pathways :
Coenzyme A Biosynthesis, Pantothenate = CoA Pathway (405206); Coenzyme A Biosynthesis, Pantothenate = CoA Pathway (468312); Metabolic Pathways (131985); Pantothenate And CoA Biosynthesis Pathway (1093); Pantothenate And CoA Biosynthesis Pathway (401); Pantothenate And Coenzyme A Biosynthesis I Pathway (61); Pantothenate And Coenzyme A Biosynthesis I Pathway (138355); Phosphopantothenate Biosynthesis I Pathway (92); Phosphopantothenate Biosynthesis I Pathway (138487)
ncbi summary :
Pantothenate kinase catalyzes the first step in the biosynthesis of coenzyme A, an essential cofactor that is involved in many reactions. [More information is available at EcoCyc: EG10922].
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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