product summary
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company name :
MyBioSource
product type :
protein
product name :
OLA1, 1-396aa Human, His tag, E Coli
catalog :
MBS204751
quantity :
0.1 mg
price :
375 USD
more info or order :
product information
catalog number :
MBS204751
products type :
Recombinant Protein
products full name :
OLA1, 1-396aa Human, His tag, E Coli
products short name :
OLA1
products name syn :
Obg-like ATPase 1; DOC45; GBP45; GTBP9; GTPBP9; PTD004
other names :
obg-like ATPase 1 isoform 1; Obg-like ATPase 1; obg-like ATPase 1; DNA damage-regulated overexpressed in cancer 45 protein; GTP-binding protein 9 (putative); GTP-binding protein PTD004; OLA1; homologous yeast-44.2 protein; Obg-like ATPase 1; DNA damage-regulated overexpressed in cancer 45; DOC45; GTP-binding protein 9
products gene name :
OLA1
other gene names :
OLA1; OLA1; DOC45; GBP45; GTBP9; GTPBP9; PTD004; DOC45
uniprot entry name :
OLA1_HUMAN
sequence length :
396
sequence :
MGSSHHHHHH SSGLVPRGSH MGSHMPPKKG GDGIKPPPII GRFGTSLKIG IVGLPNVGKS TFFNVLTNSQ ASAENFPFCT IDPNESRVPV PDERFDFLCQ YHKPASKIPA FLNVVDIAGL VKGAHNGQGL GNAFLSHISA CDGIFHLTRA FEDDDITHVE GSVDPIRDIE IIHEELQLKD EEMIGPIIDK LEKVAVRGGD KKLKPEYDIM CKVKSWVIDQ KKPVRFYHDW NDKEIEVLNK HLFLTSKPMV YLVNLSEKDY IRKKNKWLIK IKEWVDKYDP GALVIPFSGA LELKLQELSA EERQKYLEAN MTQSALPKII KAGFAALQLE YFFTAGPDEV RAWTIRKGTK APQAAGKIHT DFEKGFIMAE VMKYEDFKEE GSENAVKAAG KYRQQGRNYI VEDGDIIFFK FNTPQQPKKK
purity :
> 95% by SDS - PAGE
form :
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Enzymes & Proteases
products description :
OLA1, also known as obg-like ATPase 1, functions as a negative regulator of the cellular antioxidant response independent of transcriptional processes. OLA1 suppresses the antioxidant response through nontranscriptional mechanisms. Recombinant human OLA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
products references :
Choudhary C., et al. (2009) Science. 325:834-840. Koller-Eichhorn R., et al. (2007) J. Biol. Chem. 282:19928-19937
ncbi gi num :
58761500
ncbi acc num :
NP_037473
ncbi gb acc num :
NM_013341.3
ncbi mol weight :
47.3 kDa (420aa), confirmed by MALDI-TOF
uniprot summary :
OLA1: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. Belongs to the GTP1/OBG family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 3.6.3.-; Hydrolase; Nucleolus. Chromosomal Location of Human Ortholog: 2q31.1. Cellular Component: centrosome; membrane; cytoplasm; nucleolus. Molecular Function: protein binding; GTP binding; metal ion binding; ATPase activity; ribosome binding; ATP binding; ribosomal large subunit binding. Biological Process: metabolic process
size1 :
0.1 mg
price1 :
375 USD
size2 :
0.5 mg
price2 :
925
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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