product summary
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company name :
MyBioSource
product type :
protein
product name :
NT5C2, 1-561aa, Human, His tag E Coli
catalog :
MBS204746
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS204746 image 1
product information
catalog number :
MBS204746
products type :
Recombinant Protein
products full name :
NT5C2, 1-561aa, Human, His tag E Coli
products short name :
[NT5C2]
products name syn :
[Cytosolic purine 5'-nucleotidase; cN-II; GMP. NT5B; PNT5]
other names :
[cytosolic purine 5'-nucleotidase isoform 1; Cytosolic purine 5'-nucleotidase; cytosolic purine 5'-nucleotidase; 5'-nucleotidase, cytosolic II; Cytosolic 5'-nucleotidase II]
products gene name :
[NT5C2]
other gene names :
[NT5C2; NT5C2; GMP; NT5B; PNT5; SPG45; SPG65; cN-II; NT5B; NT5CP; PNT5]
host :
E Coli
sequence length :
561
sequence :
MGSSHHHHHH SSGLVPRGSH MSTSWSDRLQ NAADMPANMD KHALKKYRRE AYHRVFVNRS LAMEKIKCFG FDMDYTLAVY KSPEYESLGF ELTVERLVSI GYPQELLSFA YDSTFPTRGL VFDTLYGNLL KVDAYGNLLV CAHGFNFIRG PETREQYPNK FIQRDDTERF YILNTLFNLP ETYLLACLVD FFTNCPRYTS CETGFKDGDL FMSYRSMFQD VRDAVDWVHY KGSLKEKTVE NLEKYVVKDG KLPLLLSRMK EVGKVFLATN SDYKYTDKIM TYLFDFPHGP KPGSSHRPWQ SYFDLILVDA RKPLFFGEGT VLRQVDTKTG KLKIGTYTGP LQHGIVYSGG SSDTICDLLG AKGKDILYIG DHIFGDILKS KKRQGWRTFL VIPELAQELH VWTDKSSLFE ELQSLDIFLA ELYKHLDSSS NERPDISSIQ RRIKKVTHDM DMCYGMMGSL FRSGSRQTLF ASQVMRYADL YAASFINLLY YPFSYLFRAA HVLMPHESTV EHTHVDINEM ESPLATRNRT SVDFKDTDYK RHQLTRSISE IKPPNLFPLA PQEITHCHDE DDDEEEEEEE E
purity :
> 90% by SDS-PAGE
form :
Liquid. 20mM Tris-HCl Buffer (pH 8.0) containing 30% glycerol, 0.1M NaCl, 1mM DTT, 0.1mM PMSF
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
products categories :
Enzymes & Proteases
products description :
NT5C2, also known as NT5B or PNT5, has an essential role in the maintenance of purine/pyrimidine nucleotides. It contains a phosphotransferase active site that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates. In addition, it regulates the level of inosine monophosphate (IMP) and guanosine monophosphate (GMP) pools within cells via hydrolysis. Recombinant human NT5C2 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography.
products references :
Oka J. et al. (1994) Biochem. Biophys. Res. Commun. 205: 917-922.; Wallde K. et al. (2007) J Biol Chem. 282: 17828-17836.
ncbi gi num :
6912598
ncbi acc num :
NP_036361
ncbi gb acc num :
NM_012229.4
uniprot acc num :
P49902
ncbi mol weight :
67.1 kDa (581aa)
ncbi pathways :
Abacavir Metabolism Pathway (1270228); Abacavir Transport And Metabolism Pathway (1270226); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Nucleotides Pathway (1270133); Nicotinate And Nicotinamide Metabolism Pathway (83014); Nicotinate And Nicotinamide Metabolism Pathway (400); Purine Catabolism Pathway (1270137); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (1270134)
ncbi summary :
This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011]
uniprot summary :
May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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