product summary
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company name :
MyBioSource
product type :
protein
product name :
TIFA, 1-184aa, Human, His tag, E Coli
catalog :
MBS204665
quantity :
0.05 mg
price :
375 USD
more info or order :
product information
catalog number :
MBS204665
products type :
Recombinant Protein
products full name :
TIFA, 1-184aa, Human, His tag, E Coli
products short name :
TIFA
products name syn :
TRAF-interacting protein with FHA domain-containing protein A; T2BP; T6BP; TIFAA
other names :
TRAF-interacting protein with FHA domain-containing protein A; TRAF-interacting protein with FHA domain-containing protein A; TRAF-interacting protein with FHA domain-containing protein A; TRAF-interacting protein with a forkhead-associated domain; TRAF2 binding protein; TRAF2-binding protein; TRAF6 binding protein; putative MAPK-activating protein PM14; putative NF-kappa-B-activating protein 20; TRAF-interacting protein with forkhead-associated domain; Putative MAPK-activating protein PM14; Putative NF-kappa-B-activating protein 20; TRAF2-binding protein
products gene name :
TIFA
other gene names :
TIFA; TIFA; T2BP; T6BP; TIFAA; T2BP
uniprot entry name :
TIFA_HUMAN
sequence length :
184
sequence :
MGSSHHHHHH SSGLVPRGSH MGSHMTSFED ADTEETVTCL QMTVYHPGQL QCGIFQSISF NREKLPSSEV VKFGRNSNIC HYTFQDKQVS RVQFSLQLFK KFNSSVLSFE IKNMSKKTNL IVDSRELGYL NKMDLPYRCM VRFGEYQFLM EKEDGESLEF FETQFILSPR SLLQENNWPP HRPIPEYGTY SLCSSQSSSP TEMDENES
purity :
> 90% by SDS - PAGE
form :
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Signal Transduction
products description :
TIFA, also known as TRAF-interacting protein with FHA domain-containing protein A, is an adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. This protein induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. Recombinant human TIFA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
products references :
Takatsuna H., et al. (2003) J. Biol. Chem. 278:12144-12150. Ea C.-K., et al. (2004) Proc. Natl. Acad. Sci. u.S.A. 101:15318-15323
ncbi gi num :
33563370
ncbi acc num :
NP_443096
ncbi gb acc num :
NM_052864.2
ncbi mol weight :
24.0 kDa (208aa) confirmed by MALDI-TOF
ncbi pathways :
TNF-alpha/NF-kB Signaling Pathway 198884
size :
0.05 mg
price :
375 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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