product summary
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company name :
MyBioSource
product type :
protein
product name :
ACADL, 31-430aa, Human, His tag, E Coli
catalog :
MBS204531
quantity :
0.05 mg
price :
375 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS204531
products type :
Recombinant Protein
products full name :
ACADL, 31-430aa, Human, His tag, E Coli
products short name :
ACADL
products name syn :
Acyl-CoA dehydrogenase; long chain; ACAD4; FLJ94052; LCAD
other names :
long-chain specific acyl-CoA dehydrogenase, mitochondrial; Long-chain specific acyl-CoA dehydrogenase, mitochondrial; long-chain specific acyl-CoA dehydrogenase, mitochondrial; acyl-Coenzyme A dehydrogenase, long chain; acyl-CoA dehydrogenase, long chain
products gene name :
ACADL
other gene names :
ACADL; ACADL; LCAD; ACAD4; LCAD
uniprot entry name :
ACADL_HUMAN
sequence length :
430
sequence :
MGSSHHHHHH SSGLVPRGSH MGGEERLETP SAKKLTDIGI RRIFSPEHDI FRKSVRKFFQ EEVIPHHSEW EKAGEVSREV WEKAGKQGLL GVNIAEHLGG IGGDLYSAAI VWEEQAYSNC SGPGFSIHSG IVMSYITNHG SEEQIKHFIP QMTAGKCIGA IAMTEPGAGS DLQGIKTNAK KDGSDWILNG SKVFISNGSL SDVVIVVAVT NHEAPSPAHG ISLFLVENGM KGFIKGRKLH KMGLKAQDTA ELFFEDIRLP ASALLGEENK GFYYIMKELP QERLLIADVA ISASEFMFEE TRNYVKQRKA FGKTVAHLQT VQHKLAELKT HICVTRAFVD NCLQLHEAKR LDSATACMAK YWASELQNSV AYDCVQLHGG WGYMWEYPIA KAYVDARVQP IYGGTNEIMK ELIAREIVFD K
purity :
> 85 % by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.
concentration :
1 mg/ml (determined by Bradford)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Cancer
products description :
ACADL belongs to the acyl-CoA dehydrogenase family, existing as a homotetramer. It is involved in the catabolism of fatty acids and amino acids and they provide a major source of energy for the heart and skeletal muscle. Defect in the gene encoding ACADL leads to non-ketotic hypoglycemia and hypotonia, muscle weakness. Recombinant human ACADL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
products references :
Maher AC., et al. (2010) Mol Genet Metab. 100(2):163-7. Wanders RJ., et al. (1998) Biochim Biophys Acta. 1393(1):35-40.
ncbi gi num :
4501857
ncbi acc num :
NP_001599
ncbi gb acc num :
NM_001608.3
ncbi mol weight :
46.7 kDa (421aa), confirmed by MALDI-TOF
ncbi pathways :
Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway 106126!!Beta Oxidation Of Myristoyl-CoA To Lauroyl-CoA Pathway 106125!!Fatty Acid Beta Oxidation Pathway 198865!!Fatty Acid Degradation Pathway 82935!!Fatty Acid Degradation Pathway 296!!Fatty Acid Metabolism Pathway 868084!!Fatty Acid Metabolism Pathway 878045!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Metabolic Pathways 132956!!Metabolism Pathway 477135
ncbi summary :
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008]
size :
0.05 mg
price :
375 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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