product summary
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company name :
MyBioSource
product type :
protein
product name :
SERTAD1, 1-236aa, Human, His tag, E Coli
catalog :
MBS204516
quantity :
0.02 mg
price :
310 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS204516
products type :
Recombinant Protein
products full name :
SERTAD1, 1-236aa, Human, His tag, E Coli
products short name :
SERTAD1
products name syn :
SERTA domain-containing protein; SEI1; TRIP-Br1
other names :
SERTA domain-containing protein 1; SERTA domain-containing protein 1; SERTA domain-containing protein 1; CDK4-binding protein p34SEI; CDK4-binding protein p34SEI1; SEI-1; transcriptional regulator interacting with the PHD-bromodomain 1; SERTA domain containing 1; CDK4-binding protein p34SEI1; SEI-1; Transcriptional regulator interacting with the PHD-bromodomain 1; TRIP-Br1
products gene name :
SERTAD1
other gene names :
SERTAD1; SERTAD1; SEI1; TRIP-Br1; SEI1; SEI-1; TRIP-Br1
uniprot entry name :
SRTD1_HUMAN
sequence length :
236
sequence :
MGSSHHHHHH SSGLVPRGSH MGSHMLSKGL KRKREEEEEK EPLAVDSWWL DPGHTAVAQA PPAVASSSLF DLSVLKLHHS LQQSEPDLRH LVLVVNTLRR IQASMAPAAA LPPVPSPPAA PSVADNLLAS SDAALSASMA SLLEDLSHIE GLSQAPQPLA DEGPPGRSIG GAAPSLGALD LLGPATGCLL DDGLEGLFED IDTSMYDNEL WAPASEGLKP GPEDGPGKEE APELDEAELD YLMDVLVGTQ ALERPPGPGR
purity :
> 85% by SDS - PAGE
form :
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 1mM DTT
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Epigenomics
products description :
SERTAD1, also known as SERTA domain-containing protein, acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. This protein stimulates E2F-1/DP-1 transcriptional activity. Recombinant human SERTAD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
products references :
Hsu S.-I., et al. (2001) EMBO J. 20:2273-2285. Sugimoto M., et al. (1999) Genes Dev. 13:3027-3033
ncbi gi num :
153792060
ncbi acc num :
NP_037508
ncbi gb acc num :
NM_013376.3
ncbi mol weight :
27.3 kDa (260aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)
uniprot summary :
SERTAD1: Acts at E2F-responsive promoters to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F-1/DP-1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a). Protein type: Cell cycle regulation; Transcription regulation. Chromosomal Location of Human Ortholog: 19q13.1-q13.2. Molecular Function: protein binding. Biological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of cell proliferation; regulation of cyclin-dependent protein kinase activity
size1 :
0.02 mg
price1 :
310 USD
size2 :
0.1 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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