product summary
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company name :
MyBioSource
product type :
protein
product name :
GNAI2, 1-355aa, Human, His tag, E Coli
catalog :
MBS204388
quantity :
0.1 mg
price :
375 USD
more info or order :
image
image 1 :
product information
catalog number :
MBS204388
products type :
Recombinant Protein
products full name :
GNAI2, 1-355aa, Human, His tag, E Coli
products short name :
[GNAI2]
products name syn :
[Guanine nucleotide-binding protein G (i) subunit alpha-2; GIP; GNAI2B; H_LuCA15.1; H_LuCA16.1]
other names :
[guanine nucleotide-binding protein G(i) subunit alpha-2 isoform 1; Guanine nucleotide-binding protein G(i) subunit alpha-2; guanine nucleotide-binding protein G(i) subunit alpha-2; G protein subunit alpha i2; Adenylate cyclase-inhibiting G alpha protein]
products gene name :
[GNAI2]
other gene names :
[GNAI2; GNAI2; GIP; GNAI2B; H_LUCA15.1; H_LUCA16.1; GNAI2B]
host :
E Coli
sequence length :
355
sequence :
MGSSHHHHHH SSGLVPRGSH MGCTVSAEDK AAAERSKMID KNLREDGEKA AREVKLLLLG AGESGKSTIV KQMKIIHEDG YSEEECRQYR AVVYSNTIQS IMAIVKAMGN LQIDFADPSR ADDARQLFAL SCTAEEQGVL PDDLSGVIRR LWADHGVQAC FGRSREYQLN DSAAYYLNDL ERIAQSDYIP TQQDVLRTRV KTTGIVETHF TFKDLHFKMF DVGGQRSERK KWIHCFEGVT AIIFCVALSA YDLVLAEDEE MNRMHESMKL FDSICNNKWF TDTSIILFLN KKDLFEEKIT HSPLTICFPE YTGANKYDEA ASYIQSKFED LNKRKDTKEI YTHFTCATDT KNVQFVFDAV TDVIIKNNLK DCGLF
purity :
> 90% by SDS-PAGE
form :
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
other info1 :
Antigen Species: Human. Tag Information: His-tag
products categories :
Signal Transduction
products description :
GNAI2 is an alpha subunit of guanine nucleotide binding proteins (G proteins). The protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only two are known so far. Recombinant human GNAI2 proetin, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
products references :
Magovcevic I, Ang SL, et al. (1992). Genomics. 12 (1):125-9.; Damaj BB, McColl SR, et al. (1996). FASEB J. Oct;10 (12):1426-34.
ncbi gi num :
4504041
ncbi acc num :
NP_002061
ncbi gb acc num :
NM_002070.3
uniprot acc num :
P04899
ncbi mol weight :
42 kDa (375aa) confirmed by MALDI-TOF
ncbi pathways :
ADP Signalling Through P2Y Purinoceptor 12 Pathway (1269353); Activation Of GABAB Receptors Pathway (1268816); Adenylate Cyclase Inhibitory Pathway (1268818); Adrenaline,noradrenaline Inhibits Insulin Secretion Pathway (1270103); Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696); Alcoholism Pathway (585563); Alcoholism Pathway (587116); Apelin Signaling Pathway (1492886); Axon Guidance Pathway (83065)
ncbi summary :
The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
uniprot summary :
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division.
size1 :
0.1 mg
price1 :
375 USD
size2 :
0.5 mg
price2 :
925
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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