product summary
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company name :
MyBioSource
product type :
protein
product name :
NRK1, 1-199aa, Human, His tag, E Coli
catalog :
MBS204376
quantity :
0.1 mg
price :
310 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS204376 image 1
product information
catalog number :
MBS204376
products type :
Recombinant Protein
products full name :
NRK1, 1-199aa, Human, His tag, E Coli
products short name :
[NRK1]
products name syn :
[nicotinamide riboside kinase 1 isoform 1; bA235O14.2; NRK1; RP11-235O14.2]
other names :
[nicotinamide riboside kinase 1 isoform 1; Nicotinamide riboside kinase 1; Nicotinic acid riboside kinase 1 (EC:2.7.1.173]
products gene name :
[NRK1]
other gene names :
[NMRK1; C9orf95; NRK1; RNK 1]
host :
E Coli
sequence length :
199
sequence :
MGSSHHHHHH SSGLVPRGSH MGSMKTFIIG ISGVTNSGKT TLAKNLQKHL PNCSVISQDD FFKPESEIET DKNGFLQYDV LEALNMEKMM SAISCWMESA RHSVVSTDQE SAEEIPILII EGFLLFNYKP LDTIWNRSYF LTIPYEECKR RRSTRVYQPP DSPGYFDGHV WPMYLKYRQE MQDITWEVVY LDGTKSEEDL FLQVYEDLIQ ELAKQKCLQV TA
purity :
> 90% by SDS-PAGE
form :
Liquid. In 20 mM Tris-HCl Buffer, pH8.0, 10% glycerol, 2mM DTT, 200mM NaCl
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
products categories :
Signal Transduction
products description :
NRK1 belongs to the uridine kinase family. NAD+ is essential for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADPribosyl groups used in various reactions, including those that retard aging in experimental systems. Nicotinic acid and nicotinamide were defined as the vitamin precursors of NAD+. This enzyme catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 3-deazaguanosine. Recombinant human NRK1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
products references :
Bieganowski P, et al. (2004) Cell. 14;117 (4):495-502.; Khan JA, et al. (2007) Structure. 15 (8):1005-13.
ncbi gi num :
8923530
ncbi acc num :
NP_060351
ncbi gb acc num :
NM_017881.2
uniprot acc num :
Q9NWW6
ncbi mol weight :
25.6kDa (222aa), confirmed by MALDI-TOF
ncbi pathways :
Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Vitamins And Cofactors Pathway (1270144); Metabolism Of Water-soluble Vitamins And Cofactors Pathway (1270145); Nicotinate And Nicotinamide Metabolism Pathway (83014); Nicotinate And Nicotinamide Metabolism Pathway (400); Nicotinate Metabolism Pathway (1270154)
uniprot summary :
Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 3-deazaguanosine.
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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