catalog number :
MBS204375
products type :
Recombinant Protein
products full name :
XAGE1A, 1-81aa, Human, His tag, E Coli
products short name :
XAGE1A
products name syn :
G antigen family D member 2; CT12.1; CT12.1A; CTP9; GAGED2; XAGE1; XAGE1B; XAGE1C; XAGE1D; XAGE1E
products gene name :
XAGE1A
sequence :
MGSSHHHHHH SSGLVPRGSH MGSMESPKKK NQQLKVGILH LGSRQKKIRI QLRSQCATWK VICKSCISQT PGINLDLGSG VKVKIIPKEE HCKMPEAGEE QPQV
purity :
> 85% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 2mM DTT
concentration :
0.25 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Cancer
products description :
G antigen family D member 2, also known as XAGE1A, is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in Ewing's sarcoma, alveolar rhabdomyosarcoma and normal testis. The protein encoded by this gene contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT(cancer-testis) antigens. Recombinant human XAGE1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Egland K.A., et al. (2002) Mol. Cancer Ther. 1:441-450. Sato S., et al. (2007) Cancer Immun. 7:5-5
ncbi acc num :
NP_001091061
ncbi gb acc num :
NM_001097592.2
ncbi mol weight :
11.5 kDa (104aa) confirmed by MALDI-TOF