product summary
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company name :
MyBioSource
product type :
antibody
product name :
Cy3-Linked Polyclonal Antibody to Coilin (COIL)
catalog :
MBS2043190
quantity :
0.1 mg
price :
375 USD
clonality :
polyclonal
host :
rabbit
conjugate :
Cy3
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS2043190
products type :
Antibody
products full name :
Cy3-Linked Polyclonal Antibody to Coilin (COIL)
products short name :
[Coilin (COIL)]
products name syn :
[CLN80; P80-Coilin]
other names :
[coilin; Coilin; coilin; coilin; p80-coilin]
products gene name :
[COIL]
other gene names :
[COIL; COIL; CLN80; p80-coilin; CLN80]
clonality :
Polyclonal
host :
Rabbit
purity :
Antigen-specific Affinity Chromatography.
form :
Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
concentration :
0.49 mg/ml
storage stability :
Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss ratewas determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition. Note: As fluorescence can photobleach when exposed to light, so the antibody must be protected from light.
tested application :
Western Blot (WB),Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF).
app notes :
Western blotting: 0.5-2 ug/mL;1:240-1000. Immunohistochemistry: 5-20 ug/mL;1:24-100. Immunocytochemistry: 5-20 ug/mL;1:24-100. Optimal working dilutions must be determined by end user
other info1 :
Organism Species: Homo sapiens (Human). Source: Antibody labeling. Label: Cy3. Traits: Liquid. Immunogen: Recombinant COIL (Ser319~Glu538) expressed in E.coli.
ncbi gi num :
4758024
ncbi acc num :
NP_004636.1
ncbi gb acc num :
NM_004645.2
ncbi summary :
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008]
uniprot summary :
coilin: an ubiquitous protein found in nuclear coiled bodies (CBS), nuclear suborganelles involved in the post-transcriptional modification of snRNPs and small nucleolar RNAs. snRNPs undergo 2'-O-methylation and pseudouridylation in CBS. Differential methylation and phosphorylation of coilin likely influences localization among nuclear bodies and the composition and assembly of CBS. Located in the interchromatin space between the nucleolus and the nucleus. Protein type: Oxidoreductase. Chromosomal Location of Human Ortholog: 17q22. Cellular Component: Cajal body; membrane; nucleolus; nucleoplasm; nucleus. Molecular Function: identical protein binding; protein binding; protein C-terminus binding
size1 :
0.1 mg
price1 :
375 USD
size2 :
0.2 mg
price2 :
580
size3 :
1 mg
price3 :
1410
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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