product summary
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company name :
MyBioSource
product type :
protein
product name :
CNN1, 1-297aa, Human, His tag, E Coli
catalog :
MBS204312
quantity :
0.1 mg
price :
310 USD
more info or order :
product information
catalog number :
MBS204312
products type :
Recombinant Protein
products full name :
CNN1, 1-297aa, Human, His tag, E Coli
products short name :
CNN1
products name syn :
Calponin-1; Sm-Calp; SMCC
other names :
calponin-1; Calponin-1; calponin-1; basic calponin; calponin H1, smooth muscle; calponins, basic; epididymis secretory protein Li 14; calponin 1, basic, smooth muscle; Basic calponin; Calponin H1, smooth muscle
products gene name :
CNN1
other gene names :
CNN1; CNN1; SMCC; Sm-Calp; HEL-S-14
uniprot entry name :
CNN1_HUMAN
sequence length :
297
sequence :
MSSAHFNRGP AYGLSAEVKN KLAQKYDHQR EQELREWIEG VTGRRIGNNF MDGLKDGIIL CEFINKLQPG SVKKINESTQ NWHQLENIGN FIKAITKYGV KPHDIFEAND LFENTNHTQV QSTLLALASM AKTKGNKVNV GVKYAEKQER KFEPGKLREG RNIIGLQMGT NKFASQQGMT AYGTRRHLYD PKLGTDQPLD QATISLQMGT NKGASQAGMT APGTKRQIFE PGLGMEHCDT LNVSLQMGSN KGASQRGMTV YGLPRQVYDP KYCLTPEYPE LGEPAHNHHA HNYYNSALEH HHHHH
purity :
> 90% by SDS - PAGE
form :
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.15M NaCl, 1mM DTT
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Actin & Myosin Related
products description :
CNN1, also known as calponin-1, belongs to the calponin family. CNN1 is thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Recombinant human CNN1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography.
products references :
Maguchi M., et al. (1995) Biochem. Biophys. Res. Commun. 217:238-244. Miano J.M., et al. (1997) Gene. 197:215-224
ncbi gi num :
21361120
ncbi acc num :
NP_001290
ncbi gb acc num :
NM_001299.4
ncbi mol weight :
34.2 kDa (305aa) confirmed by MALDI-TOF
ncbi pathways :
Endothelin Pathway (672453); Myometrial Relaxation And Contraction Pathways (198759)
uniprot summary :
calponin 1: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. Protein type: Myosin-binding; Contractile; Motility/polarity/chemotaxis; Actin-binding. Chromosomal Location of Human Ortholog: 19p13.2-p13.1. Cellular Component: focal adhesion; cytoskeleton. Molecular Function: calmodulin binding; actin binding. Biological Process: regulation of smooth muscle contraction; actomyosin structure organization and biogenesis
size1 :
0.1 mg
price1 :
310 USD
size2 :
0.5 mg
price2 :
720
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
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