product summary
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company name :
MyBioSource
product type :
protein
product name :
RBP1, 1-197aa, Human, His tag, E Coli
catalog :
MBS204300
quantity :
0.05 mg
price :
310 USD
more info or order :
product information
catalog number :
MBS204300
products type :
Recombinant Protein
products full name :
RBP1, 1-197aa, Human, His tag, E Coli
products short name :
RBP1
products name syn :
retinol binding protein 1; CRABP-I; CRBP; CRBP1; CRBPI; RBPC
other names :
retinol-binding protein 1 isoform a; Retinol-binding protein 1; retinol-binding protein 1; CRBP-I; cellular retinol-binding protein I; retinol-binding protein 1, cellular; retinol binding protein 1, cellular; Cellular retinol-binding protein; CRBP; Cellular retinol-binding protein I; CRBP-I
products gene name :
RBP1
other gene names :
RBP1; RBP1; CRBP; RBPC; CRBP1; CRBPI; CRABP-I; CRBP1; CRBP; CRBP-I
uniprot entry name :
RET1_HUMAN
sequence length :
197
sequence :
MGSSHHHHHH SSGLVPRGSH MGSMDPPAGF VRAGNPAVAA PQSPLSPEGA HFRAAHHPRS TGSRCPGSLQ PSRPLVANWL QSLPEMPVDF TGYWKMLVNE NFEEYLRALD VNVALRKIAN LLKPDKEIVQ DGDHMIIRTL STFRNYIMDF QVGKEFEEDL TGIDDRKCMT TVSWDGDKLQ CVQKGEKEGR GWTQWIEGDE LHLEMRVEGV VCKQVFKKVQ
purity :
> 90% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200mM NaCl
concentration :
0.5mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Signal Transduction
products description :
RBP1 (Retinol binding protein 1) belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. RBP1 is the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. RBP1 can also act as a bridging molecule to recruit histone deacetylases (HDACs), proteins that function as potent regulators of gene expression. This protein is detected in nearly all the tissues with higher expression in adult ovary, pancreas, pituitary gland and adrenal gland, and fetal liver. Recombinant human RBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Lai, A., et al. (2001) Mol. Cell. Biol. 21: 2918-2932. Folli C., et al. (2001) Proc. Natl. Acad. Sci. u.S.A. 98:3710-3715
ncbi gi num :
195976807
ncbi acc num :
NP_002890
ncbi gb acc num :
NM_002899.3
ncbi mol weight :
24.7kDa (220aa), confirmed by MALDI-TOF
ncbi pathways :
Disease Pathway (530764); Diseases Associated With Visual Transduction Pathway (771581); RB In Cancer Pathway (920977); Retinoic Acid Receptors-mediated Signaling Pathway (138039); Retinoid Cycle Disease Events Pathway (771582); Retinoid Metabolism And Transport Pathway (187208); Signal Transduction Pathway (477114); The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway (771585); Visual Phototransduction Pathway (771584); Vitamin A And Carotenoid Metabolism Pathway (198785)
ncbi summary :
This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
uniprot summary :
RBP1: Intracellular transport of retinol. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Chromosomal Location of Human Ortholog: 3q23. Cellular Component: cytosol. Molecular Function: retinoid binding; transporter activity; retinol binding; retinal binding. Biological Process: phototransduction, visible light; transport; retinoid metabolic process; vitamin A metabolic process
size1 :
0.05 mg
price1 :
310 USD
size2 :
0.25 mg
price2 :
720
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
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