product summary
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company name :
MyBioSource
product type :
protein
product name :
SIL1, 32-461aa, Human, His tag, E Coli
catalog :
MBS204276
quantity :
0.02 mg
price :
310 USD
more info or order :
MyBioSource product webpage
image
image 1 :
MyBioSource MBS204276 image 1
product information
catalog number :
MBS204276
products type :
Recombinant Protein
products full name :
SIL1, 32-461aa, Human, His tag, E Coli
products short name :
[SIL1]
products name syn :
[Nucleotide exchange factor SIL1; BAP; MSS; uLG5]
other names :
[nucleotide exchange factor SIL1; Nucleotide exchange factor SIL1; nucleotide exchange factor SIL1; SIL1 nucleotide exchange factor; BiP-associated protein; BAP]
products gene name :
[SIL1]
other gene names :
[SIL1; SIL1; BAP; MSS; ULG5; BAP]
host :
E Coli
sequence length :
461
sequence :
MHQNLKEFAL TNPEKSSTKE TERKETKAEE ELDAEVLEVF HPTHEWQALQ PGQAVPAGSH VRLNLQTGER EAKLQYEDKF RNNLKGKRLD INTNTYTSQD LKSALAKFKE GAEMESSKED KARQAEVKRL FRPIEELKKD FDELNVVIET DMQIMVRLIN KFNSSSSSLE EKIAALFDLE YYVHQMDNAQ DLLSFGGLQV VINGLNSTEP LVKEYAAFVL GAAFSSNPKV QVEAIEGGAL QKLLVILATE QPLTAKKKVL FALCSLLRHF PYAQRQFLKL GGLQVLRTLV QEKGTEVLAV RVVTLLYDLV TEKMFAEEEA ELTQEMSPEK LQQYRQVHLL PGLWEQGWCE ITAHLLALPE HDAREKVLQT LGVLLTTCRD RYRQDPQLGR TLASLQAEYQ VLASLELQDG EDEGYFQELL GSVNSLLKEL RLEHHHHHH
purity :
> 90% by SDS-PAGE
form :
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
concentration :
0.5 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
image1 heading :
SDS-Page
other info1 :
Antigen Species: Human. Tag Information: His-tag
products categories :
Heat Shock Proteins
products description :
Nucleotide exchange factor, also known as SIL1, is a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Recombinant human SIL1 protein, fused to His-tag at C-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
products references :
Chung KT., et al. (2002) J Biol Chem. 277 (49):47557-63.; Senderek J., et al. (2005) Nat Genet. 37 (12): 1312-4.
ncbi gi num :
11968009
ncbi acc num :
NP_071909
ncbi gb acc num :
NM_022464.4
uniprot acc num :
Q9H173
ncbi mol weight :
50 kDa (439aa)
ncbi pathways :
Protein Processing In Endoplasmic Reticulum Pathway (167325); Protein Processing In Endoplasmic Reticulum Pathway (167190)
ncbi summary :
This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
uniprot summary :
Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.
size1 :
0.02 mg
price1 :
310 USD
size2 :
0.1 mg
price2 :
720
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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