FCGR1A, 16-292aa, Human, His tag, E Coli | MyBioSource MBS204214 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

FCGR1A, 16-292aa, Human, His tag, E Coli

catalog :

MBS204214

quantity :

0.02 mg

price :

310 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS204214

products type :

Recombinant Protein

products full name :

FCGR1A, 16-292aa, Human, His tag, E Coli

products short name :

FCGR1A

products name syn :

High affinity immunoglobulin gamma Fc receptor I; CD64; CD64A; FCRI; IGFR1

other names :

high affinity immunoglobulin gamma Fc receptor I; High affinity immunoglobulin gamma Fc receptor I; high affinity immunoglobulin gamma Fc receptor I; Fc fragment of IgG, high affinity Ia, receptor for (CD64); Fc gamma receptor; Fc-gamma RI; Fc-gamma receptor I A1; IgG Fc receptor I; fc-gamma RIA; fcgammaRIa; Fc fragment of IgG, high affinity Ia, receptor (CD64); Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD_antigen: CD64

products gene name :

FCGR1A

other gene names :

FCGR1A; FCGR1A; CD64; FCRI; CD64A; IGFR1; FCG1; FCGR1; IGFR1; IgG Fc receptor I; FcRI; FcgammaRIa

uniprot entry name :

FCGR1_HUMAN

sequence length :

374

sequence :

MGSSHHHHHH SSGLVPRGSH MGSHMQVDTT KAVITLQPPW VSVFQEETVT LHCEVLHLPG SSSTQWFLNG TATQTSTPSY RITSASVNDS GEYRCQRGLS GRSDPIQLEI HRGWLLLQVS SRVFTEGEPL ALRCHAWKDK LVYNVLYYRN GKAFKFFHWN SNLTILKTNI SHNGTYHCSG MGKHRYTSAG ISVTVKELFP APVLNASVTS PLLEGNLVTL SCETKLLLQR PGLQLYFSFY MGSKTLRGRN TSSEYQILTA RREDSGLYWC EAATEDGNVL KRSPELELQV LGLQLPTPVW FH

purity :

> 85% by SDS - PAGE

form :

Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT

concentration :

0.5 mg/ml (determined by Bradford assay)

storage stability :

Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.

tested application :

SDS-PAGE

other info1 :

Antigen Species: Human. Tag: His-tag

other info2 :

Expression System: E Coli

products categories :

Immunology

products description :

FCGR1A, also known as CD64, belongs to the immunoglobulin superfamily. This protein is high affinity receptor for the Fc region of immunoglobulins gamma. It plays an important role in both innate and adaptive immune response. Recombinant human FCGR1A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques

products references :

Ernst L.K., et al. (1998) Mol. Immunol. 35:943-954. van Vugt M.J., et al. (1999) Blood. 94:808-817

ncbi gi num :

10835133

ncbi acc num :

NP_000557

ncbi gb acc num :

NM_000566.3

ncbi mol weight :

33.8 kDa (302aa) confirmed by MALDI-TOF

ncbi pathways :

Adaptive Immune System Pathway (366160); Antigen Processing-Cross Presentation Pathway (477122); Class I MHC Mediated Antigen Processing Presentation Pathway (366161); Cross-presentation Of Soluble Exogenous Antigens (endosomes) Pathway (477126); Cytokine Signaling In Immune System Pathway (366171); FCGR Activation Pathway (771578); Fc Gamma R-mediated Phagocytosis Pathway (114228); Fc Gamma R-mediated Phagocytosis Pathway (106590); Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway (771577); Hematopoietic Cell Lineage Pathway (83078)

ncbi summary :

This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]

uniprot summary :

FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 1q21.2-q21.3. Cellular Component: early endosome membrane; integral to membrane; plasma membrane. Molecular Function: protein binding; IgG binding; receptor signaling protein activity. Biological Process: antigen processing and presentation of peptide antigen via MHC class I; cytokine and chemokine mediated signaling pathway; innate immune response; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; antigen processing and presentation of exogenous peptide antigen via MHC class I; immune response; phagocytosis, engulfment; signal transduction

size1 :

0.02 mg

price1 :

310 USD

size2 :

0.1 mg

price2 :

720

more info or order :

MyBioSource product webpage