product summary
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company name :
MyBioSource
product type :
protein
product name :
DYNLT1, 1-113aa, Human, His tag, E Coli
catalog :
MBS204094
quantity :
0.1 mg
price :
310 USD
more info or order :
product information
catalog number :
MBS204094
products type :
Recombinant Protein
products full name :
DYNLT1, 1-113aa, Human, His tag, E Coli
products short name :
DYNLT1
products name syn :
Dynein light chain Tctex-type 1; CW-1; TCTEL1; tctex-1
other names :
dynein light chain Tctex-type 1 isoform 1; Dynein light chain Tctex-type 1; dynein light chain Tctex-type 1; T-complex testis-specific protein 1 homolog; t-complex-associated-testis-expressed 1-like 1; dynein, light chain, Tctex-type 1; Protein CW-1; T-complex testis-specific protein 1 homolog
products gene name :
DYNLT1
other gene names :
DYNLT1; DYNLT1; CW-1; TCTEL1; tctex-1; TCTEL1; TCTEX-1; TCTEX1
uniprot entry name :
DYLT1_HUMAN
sequence length :
113
sequence :
MGSSHHHHHH SSGLVPRGSH MEDYQAAEET AFVVDEVSNI VKEAIESAIG GNAYQHSKVN QWTTNVVEQT LSQLTKLGKP FKYIVTCVIM QKNGAGLHTA SSCFWDSSTD GSCTVRWENK TMYCIVSAFG LSI
purity :
> 95% by SDS - PAGE
form :
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.1M NaCl
concentration :
1 mg/ml (determined by Bradford assay)
storage stability :
Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.
tested application :
SDS-PAGE
other info1 :
Antigen Species: Human. Tag: His-tag
other info2 :
Expression System: E Coli
products categories :
Cytoskeleton
products description :
Dynein light chain Tctex-type 1, also known as DYNLT1, belongs to the dynein light chain Tctex-type family. DYNLT1 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. DYNLT1 is a dynein light chain involved in cargo binding. Recombinant human DYNLT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
products references :
Asai D J., et al. (2004) J Eukaryot Microbiol. 51:23-29. He Y., et al. (2005) J Cell Biol. 168:697-703.
ncbi gi num :
5730085
ncbi acc num :
NP_006510
ncbi gb acc num :
NM_006519.3
ncbi mol weight :
14.6 kDa (133aa), confirmed by MALDI-TOF
ncbi pathways :
Lissencephaly Gene (LIS1) In Neuronal Migration And Development Pathway 137984!!Neurotrophic Factor-mediated Trk Receptor Signaling Pathway 137977
ncbi summary :
This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
size :
0.1 mg
price :
310 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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